SCHEMBL5996363

SCHEMBL5996363

CCC(C)P(=O)(C(=O)c1c(C)cccc1C)C(=O)c1c(C)cc(C(C)(C)C)cc1C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
ALPL P05186 1/20 0.35
GAA P10253 1/20 0.35
HTT P42858 1/20 0.35
TP53 P04637 1/20 0.34
THRB P10828 1/20 0.34
F2R P25116 1/20 0.34
ACHE P22303 2/20 0.33
TSHR P16473 3/20 0.32
RXRB P28702 3/20 0.32
RXRA P19793 2/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2C9 P11712 2/20 0.32
LMNA P02545 1/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5995927 0.93 ALPL (0.36) SMN1; SMN2MEN1KMT2AL3MBTL1ALPL
SCHEMBL5996841 0.91 MEN1 (0.33) SMN1; SMN2MEN1KMT2AL3MBTL1ALPL
SCHEMBL5998075 0.90 GAA (0.38) SMN1; SMN2MEN1KMT2AL3MBTL1ALPL
SCHEMBL5995414 0.89 HPGD (0.35) SMN1; SMN2MEN1KMT2AL3MBTL1ALPL
SCHEMBL6466911 0.89 L3MBTL1 (0.38) SMN1; SMN2MEN1KMT2AL3MBTL1HTT
SCHEMBL5995631 0.88 CTSS (0.37) SMN1; SMN2MEN1KMT2AL3MBTL1ALPL
SCHEMBL5996964 0.88 TAS1R3 (0.39) SMN1; SMN2MEN1KMT2AHTTTSHR
SCHEMBL5995811 0.87 KMT2A (0.39) SMN1; SMN2MEN1KMT2AL3MBTL1HTT
SCHEMBL5996657 0.87 RXFP1 (0.39) SMN1; SMN2MEN1KMT2AL3MBTL1HTT
SCHEMBL5996896 0.83 FLT1 (0.32) MEN1KMT2AL3MBTL1ALPLGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026017-B2 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-11 US disclosed
US-6969733-B2 Photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-29 US disclosed
US-6737549-B2 PHOTOINITIATORS FOR ACRYLATE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
US-20030139485-A1 Photoinitiators WOLF JEAN-PIERRE (CH) 2003-07-24 US disclosed
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation WOLF JEAN-PIERRE (CH) 2003-07-10 US disclosed
US-20020026049-A1 Photoinitiators for acrylate coatings CIBA SPECIALTY CHEMICALS CORP. 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139485-A1 Photoinitiators DHCR24, NR1I3, CBR1 SMN1; SMN2 3940/4885MEN1 3862/4885KMT2A 1784/4885
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation SMARCC1, ARPC5L, DHCR24 SMN1; SMN2 1663/4885MEN1 2456/4885KMT2A 761/4885
US-20020026049-A1 Photoinitiators for acrylate coatings DHCR24, NR5A1, NR2C2 SMN1; SMN2 4099/4885MEN1 3695/4885KMT2A 1577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.