Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 4/20 | 0.52 |
| ▸ | MC3R | P41968 | 4/20 | 0.52 |
| ▸ | MC1R | Q01726 | 4/20 | 0.52 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5997538 | 0.88 | MC4R (0.48) | MC4RMC3RMC1RBDKRB2ABCB1 | |
| SCHEMBL5996402 | 0.85 | BDKRB2 (0.47) | MC4RMC3RMC1RBDKRB2ABCB1 | |
| SCHEMBL14207221 | 0.84 | BDKRB2 (0.46) | MC4RMC3RMC1RBDKRB2ABCB1 | |
| SCHEMBL6338200 | 0.84 | ABCB1 (0.47) | MC4RMC3RMC1RBDKRB2ABCB1 | |
| SCHEMBL6380846 | 0.82 | BDKRB2 (0.48) | MC4RMC3RMC1RBDKRB2ABCB1 | |
| SCHEMBL6380857 | 0.82 | BDKRB2 (0.48) | MC4RMC3RMC1RBDKRB2ABCB1 | |
| SCHEMBL6380853 | 0.82 | BDKRB2 (0.48) | MC4RMC3RMC1RBDKRB2ABCB1 | |
| SCHEMBL2980458 | 0.80 | ABCB1 (0.57) | MC4RMC3RMC1RBDKRB2ABCB1 | |
| SCHEMBL1751337 | 0.80 | USP30 (0.44) | ABCB1MCL1 | |
| SCHEMBL12021345 | 0.80 | USP30 (0.44) | ABCB1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7087759-B2 | for controlling weight; pyrrolidine or piperidine compounds | THE PROCTER & GAMBLE COMPANY (US) | 2006-08-08 | — | — | US | disclosed |
| US-20060106059-A1 | Melanocortin receptor ligands | MAZUR WIESLAW A | 2006-05-18 | — | — | US | disclosed |
| EP-1390361-A4 | MELANOCORTIN RECEPTOR LIGANDS | PROCTER & GAMBLE (US) | 2005-10-05 | — | — | EP | disclosed |
| US-6911447-B2 | Melanocortin receptor ligands | THE PROCTER & GAMBLE COMPANY (US) | 2005-06-28 | — | — | US | disclosed |
| US-20040224985-A1 | Melanocortin receptor ligands | THE PROCTER & GAMBLE COMPANY | 2004-11-11 | — | — | US | disclosed |
| EP-1390361-A2 | MELANOCORTIN RECEPTOR LIGANDS | THE PROCTER & GAMBLE COMPANY (US) | 2004-02-25 | — | — | EP | disclosed |
| US-20030109556-A1 | Melanocortin receptor ligands | THE PROCTER & GAMBLE COMPANY | 2003-06-12 | — | — | US | disclosed |
| WO-2002085925-A2 | MELANOCORTIN RECEPTOR LIGANDS | THE PROCTER & GAMBLE COMPANY (US) | 2002-10-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109556-A1 | Melanocortin receptor ligands | MC3R, MC4R, MC1R | MC4R 2/4885MC3R 1/4885MC1R 3/4885 |
| US-20060106059-A1 | Melanocortin receptor ligands | MC3R, MC4R, MC1R | MC4R 2/4885MC3R 1/4885MC1R 3/4885 |
| US-20040224985-A1 | Melanocortin receptor ligands | MC3R, MC4R, MC1R | MC4R 2/4885MC3R 1/4885MC1R 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.