Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1778197 | 0.69 | HSD17B10 (0.61) | MEN1KMT2AKDM4E | |
| SCHEMBL3712362 | 0.69 | CYP1A2 (0.46) | DAGLACYP2D6CYP2C19MEN1CYP1A2 | |
| SCHEMBL18839792 | 0.69 | USP2 (0.40) | MEN1KMT2AKDM4E | |
| SCHEMBL18839781 | 0.68 | PKM (0.34) | — | |
| SCHEMBL12662755 | 0.67 | PIK3CD (0.41) | PIK3CDPIK3CAPIK3CBPIK3CGCLK1 | |
| SCHEMBL5618142 | 0.66 | TSHR (0.40) | DAGLATRPV1KDM4E | |
| SCHEMBL14417042 | 0.65 | GRIK1 (0.36) | MEN1KMT2AGRIK1GRIA1GRIA2 | |
| SCHEMBL5996863 | 0.65 | ALDH1A1 (0.36) | DAGLAKMT2AGRIK1GRIA1GRIA2 | |
| SCHEMBL22455534 | 0.65 | RAB9A (0.48) | CYP2D6 | |
| SCHEMBL19347393 | 0.65 | KMT2A (0.39) | KMT2APIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100144-A1 | FUSED BICYCLIC COMPOUNDS AS INHIBITORS FOR PI3 KINASE | MERCK SERONO S.A. (CH) | 2010-09-10 | — | — | WO | disclosed |