Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22691739 | 0.88 | MAPT (0.40) | ALDH1A1NPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL4702415 | 0.88 | MAPT (0.40) | ALDH1A1NPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL22699253 | 0.88 | ALDH1A1 (0.39) | ALDH1A1NPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL29926097 | 0.88 | MAPT (0.40) | ALDH1A1NPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL4701786 | 0.88 | MAPT (0.40) | ALDH1A1NPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL4702389 | 0.87 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL4702387 | 0.87 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL4702022 | 0.87 | MAPT (0.40) | ALDH1A1NPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL13154849 | 0.86 | ALDH1A1 (0.45) | ALDH1A1NPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL4704161 | 0.86 | ALDH1A1 (0.42) | ALDH1A1NPC1RAB9AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060247320-A1 | Compounds for inhibiting KSP kinesin activity | SCHERING CORPORATION | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247320-A1 | Compounds for inhibiting KSP kinesin activity | KIFC1, KIF5B, KIF2C | ALDH1A1 2371/4885NPC1 919/4885RAB9A 745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.