Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | CD69 | Q07108 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27883628 | 0.87 | MAOA (0.47) | MAOAMAOBCD69ACSL1 | |
| SCHEMBL4021521 | 0.86 | KMT2A (0.39) | MAOAMAOBPTGER1PTGER4PTGER3 | |
| SCHEMBL8946082 | 0.82 | PTGER1 (0.46) | PTGER1PTGER4PTGER3PTGER2KEAP1 | |
| SCHEMBL4015217 | 0.79 | AKR1B1 (0.37) | MAOAMAOBFFAR1 | |
| SCHEMBL27323570 | 0.78 | MAOA (0.38) | MAOAMAOBMTNR1AACSL1 | |
| SCHEMBL22484541 | 0.78 | MAOA (0.47) | MAOAMAOBMTNR1A | |
| SCHEMBL166877 | 0.75 | KDM4C (0.51) | PTGER1PTGER4PTGER3PTGER2KEAP1 | |
| SCHEMBL7325719 | 0.75 | MAOA (0.52) | MAOAMAOBACSL1 | |
| SCHEMBL3430852 | 0.74 | MTNR1A (0.62) | PTGER1PTGER4PTGER3PTGER2MTNR1A | |
| SCHEMBL8961832 | 0.73 | MAOA (0.48) | MAOAMAOBPTGER4PARP1CD69 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141599-B2 | Immunosuppressive effects of administration of a cyclooxygenase-2 inhibitor, a leukotriene B4 receptor inhibitor and a cyclosporin | PHARMACIA CORPORATION (US) | 2006-11-28 | — | — | US | claimed |
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| US-20120208709-A1 | GENETIC SUSCEPTIBILITY VARIANTS ASSOCIATED WITH CARDIOVASCULAR DISEASE | DECODE GENETICS EHF. (IS) | 2012-08-16 | — | — | US | disclosed |