SCHEMBL5997604

SCHEMBL5997604

NCCCC[C@H](NC(=O)[C@@H](N)CC(N)=O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.53
GSR P00390 1/20 0.49
CPB2 Q96IY4 7/20 0.44
ERAP2 Q6P179 1/20 0.43
ERAP1 Q9NZ08 1/20 0.43
LNPEP Q9UIQ6 1/20 0.43
SLC6A5 Q9Y345 1/20 0.42
NOD1 Q9Y239 1/20 0.42
SLC15A2 Q16348 1/20 0.42
GNPAT O15228 1/20 0.40
DPP8 Q6V1X1 1/20 0.40
DPP9 Q86TI2 1/20 0.40
DPP7 Q9UHL4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10700763 1.00 FOLH1 (0.53) FOLH1GSRCPB2ERAP2ERAP1
SCHEMBL11765786 1.00 FOLH1 (0.53) FOLH1GSRCPB2ERAP2ERAP1
SCHEMBL29376049 1.00 FOLH1 (0.53) FOLH1GSRCPB2ERAP2ERAP1
SCHEMBL14959945 1.00 FOLH1 (0.53) FOLH1GSRCPB2ERAP2ERAP1
SCHEMBL29663724 0.97 FOLH1 (0.50) FOLH1GSRCPB2ERAP2ERAP1
SCHEMBL30731558 0.97 FOLH1 (0.50) FOLH1GSRCPB2ERAP2ERAP1
SCHEMBL30714839 0.96 FOLH1 (0.52) FOLH1GSRCPB2ERAP2ERAP1
SCHEMBL30731559 0.94 FOLH1 (0.51) FOLH1GSRCPB2ERAP2ERAP1
SCHEMBL29960118 0.92 FOLH1 (0.46) FOLH1GSRCPB2ERAP2ERAP1
SCHEMBL30223699 0.91 FOLH1 (0.62) FOLH1GSRCPB2SLC6A5NOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117838878-A Antibody-STING agonist conjugates and their use in immunotherapy 免疫传感器治疗股份有限公司 2024-04-09 CN claimed
CN-112794881-B Anti-liver cancer tridecapeptide NKSGTYSNDDLSH and preparation method thereof 黑龙江省科学院大庆分院 2023-10-31 CN claimed
EP-4114417-A2 THERAPEUTIC AGENTS AND CONJUGATES THEREOF Beijing Xuanyi Pharmasciences Co., Ltd. (CN) 2023-01-11 EP claimed
CN-115427051-A Therapeutic agents and conjugates thereof 北京轩义医药科技有限公司 2022-12-02 CN claimed
US-20220257789-A1 ANTI-TISSUE FACTOR ANTIBODY-DRUG CONJUGATES AND RELATED METHODS EXELIXIS, INC. 2022-08-18 US claimed
EP-3999118-A1 ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY Immunesensor Therapeutics, Inc. (US) 2022-05-25 EP claimed
EP-3994150-A1 ANTI-TISSUE FACTOR ANTIBODY-DRUG CONJUGATES AND RELATED METHODS Iconic Therapeutics, Inc. (US) 2022-05-11 EP claimed
EP-3320923-B1 FLUORESCENT IMAGING AGENTS VISEN MEDICAL INC (US) 2022-04-06 EP claimed
CN-114222752-A Anti-tissue factor antibody-drug conjugates and related methods 伊科尼克治疗公司 2022-03-22 CN claimed
US-12624118-B2 Trispecific binding molecules against BCMA and uses thereof NOVARTIS AG (CH) 2026-05-12 US disclosed
US-20260042847-A1 CYSTEINE ENGINEERED ANTIBODY CONSTRUCTS, CONJUGATES AND METHODS OF USE ZYMEWORKS INC (CA) 2026-02-12 US disclosed
US-20260036547-A1 METHODS FOR DETECTING METABOLITES USING A MICROFLUIDIC-BASED CE-MS SYSTEM ASTRAZENECA AB (SE) 2026-02-05 US disclosed
US-20260035473-A1 BINDING MOLECULES AGAINST BCMA AND USES THEREOFPrivate view NOVARTIS AG (CH) 2026-02-05 US disclosed
US-20260028420-A1 ANTI-TUMOR ANTIBODIES IMMUNOME INC (US) 2026-01-29 US disclosed
CN-114222752-A Anti-tissue factor antibody-drug conjugates and related methods 伊科尼克治疗公司 2022-03-22 CN disclosed
CN-114177308-A anti-cMet antibody drug conjugates and methods of use thereof 艾伯维生物制药股份有限公司 2022-03-15 CN disclosed
CN-114173810-A Trispecific binding molecules directed against BCMA and uses thereof 诺华股份有限公司 2022-03-11 CN disclosed
CN-114025795-A Methods of treating biliary tract cancer using bispecific antigen-binding constructs targeting HER2 酵活有限公司 2022-02-08 CN disclosed
US-7148203-B2 Nucleic acid transfer vector for the introduction of nucleic acid into the DNA of a cell REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2006-12-12 US disclosed
EP-0267629-A2 Polypeptides having interleukin-1 activity KYOWA HAKKO KOGYO CO., LTD. (JP) 1988-05-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042847-A1 CYSTEINE ENGINEERED ANTIBODY CONSTRUCTS, CONJUGATES AND METHODS OF USE BCR, CLTC, CARS1 FOLH1 490/4885GSR 1406/4885CPB2 2162/4885
US-20220257789-A1 ANTI-TISSUE FACTOR ANTIBODY-DRUG CONJUGATES AND RELATED METHODS F3, F13B, TFPI FOLH1 171/4885GSR 4776/4885CPB2 331/4885
US-20260035473-A1 BINDING MOLECULES AGAINST BCMA AND USES THEREOFPrivate view BCL9, BRCA1, VCAM1 FOLH1 438/4885GSR 4473/4885CPB2 375/4885
US-12624118-B2 Trispecific binding molecules against BCMA and uses thereof CD2, CD40, CD22 FOLH1 2112/4885GSR 4343/4885CPB2 2435/4885
US-20260028420-A1 ANTI-TUMOR ANTIBODIES B4GALT1, ST6GAL1, GALNT3 FOLH1 339/4885GSR 4632/4885CPB2 467/4885
US-20260036547-A1 METHODS FOR DETECTING METABOLITES USING A MICROFLUIDIC-BASED CE-MS SYSTEM ATP5ME, ATP5MF, ATP5MK FOLH1 1926/4885GSR 986/4885CPB2 613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.