Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5997917 | 0.90 | MAPT (0.49) | ATMALDH1A1L3MBTL1MEN1MAPK1 | |
| SCHEMBL5998663 | 0.83 | KMT2A (0.42) | ATMALDH1A1L3MBTL1MEN1MAPK1 | |
| SCHEMBL5997284 | 0.82 | TNF (0.43) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL5998700 | 0.81 | ALDH1A1 (0.46) | ATMALDH1A1L3MBTL1MEN1MAPK1 | |
| SCHEMBL5998270 | 0.81 | HDAC4 (0.42) | ALDH1A1MEN1MAPK1KMT2AMAPT | |
| SCHEMBL5998010 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL29217854 | 0.79 | CA1 (0.55) | ATMALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL5998065 | 0.77 | ALOX5 (0.51) | ALDH1A1L3MBTL1MEN1KMT2ATNF | |
| SCHEMBL1720402 | 0.76 | ALDH1A1 (0.59) | ATMALDH1A1L3MBTL1MEN1MAPK1 | |
| SCHEMBL7438680 | 0.75 | L3MBTL1 (0.51) | ATMALDH1A1L3MBTL1MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7094908-B2 | Reduction of carbonyl compounds using the carbonyl reductase of Kluyveromyces marxianus | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2006-08-22 | — | — | US | disclosed |
| US-20030139464-A1 | Reduction of carbonyl compounds using the carbonyl reductase of kluyveromyces marxianus | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139464-A1 | Reduction of carbonyl compounds using the carbonyl reductase of kluyveromyces marxianus | CBR1, CBR3, DCXR | ATM 3186/4885ALDH1A1 216/4885L3MBTL1 3637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.