Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438397 | 0.82 | TDP1 (0.48) | IDO1TSHRL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL39007 | 0.79 | ALDH1A1 (0.52) | IDO1TSHRL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL13303751 | 0.78 | ALDH1A1 (0.50) | IDO1TSHRL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL9468154 | 0.77 | ALDH1A1 (0.56) | TSHRL3MBTL1TDP1ALDH1A1CYP3A4 | |
| SCHEMBL23643056 | 0.76 | MAPT (0.47) | IDO1TSHRL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL300209 | 0.74 | IDO1 (0.33) | IDO1 | |
| SCHEMBL3958017 | 0.72 | ALDH1A1 (0.44) | IDO1TSHRL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL29385988 | 0.72 | TSHR (0.58) | IDO1TSHRL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL48533 | 0.72 | TSHR (0.58) | IDO1TSHRL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL19334515 | 0.71 | MAPT (0.50) | IDO1TDP1ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060116301-A1 | Liquid phenolic sulphur-containing antioxidants | CIBA SPECIALTY CHEMICALS CORP. | 2006-06-01 | — | — | US | disclosed |
| US-4337103-A | FUNCTIONALLY TERMINATED RUBBER | HERCULES INCORPORATED (US) | 1982-06-29 | — | — | US | disclosed |
| US-3982975-A | UNCURED CARBOXYLATED RUBBER, EPOXIDE CURING AGENT, PHENYLENEDIAMINE ANTIOXIDANT | HERCULES INCORPORATED (US) | 1976-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060116301-A1 | Liquid phenolic sulphur-containing antioxidants | TST, COMT, SOD1 | IDO1 4824/4885TSHR 3191/4885L3MBTL1 1511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.