Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468154 | 0.93 | ALDH1A1 (0.56) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL39007 | 0.90 | ALDH1A1 (0.52) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL2495982 | 0.83 | TDP1 (0.54) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL6000304 | 0.82 | IDO1 (0.43) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL3958017 | 0.81 | ALDH1A1 (0.44) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL17710412 | 0.81 | TDP1 (0.52) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| Methane SCHEMBL28523284 | 0.81 | TDP1 (0.52) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL8702412 | 0.79 | TDP1 (0.47) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL21174666 | 0.79 | ALDH1A1 (0.41) | TDP1ALDH1A1TSHRCYP3A4ALOX15 | |
| SCHEMBL11528967 | 0.79 | PKM (0.49) | TDP1ALDH1A1TSHRCYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5865857-A | COLORFASTNESS; PHOTOSTABILITY | ZENECA LIMITED (GB) | 1999-02-02 | — | — | US | disclosed |
| EP-0667887-B1 | DYES | ZENECA LTD (GB) | 1998-09-23 | — | — | EP | disclosed |
| US-5660598-A | PRODUCE LIGHTFAST BLUE TO GREEN SHADES ON SYNTHETIC TEXTILES | ZENECA LIMITED (GB) | 1997-08-26 | — | — | US | disclosed |
| EP-0667887-A1 | DYES | ZENECA LIMITED (GB) | 1995-08-23 | — | — | EP | disclosed |
| WO-1994010248-A1 | DYES | ZENECA LIMITED (GB) | 1994-05-11 | — | — | WO | disclosed |