Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25344211 | 0.78 | KDM4E (0.55) | POLBHTTNPSR1KDM4EGAA | |
| SCHEMBL8590556 | 0.77 | ALDH1A1 (0.54) | POLBHTTKDM4EGAAL3MBTL1 | |
| SCHEMBL8590561 | 0.77 | ALDH1A1 (0.54) | POLBHTTKDM4EGAAL3MBTL1 | |
| SCHEMBL6002516 | 0.77 | POLB (0.43) | POLBHTTNPSR1KDM4EGAA | |
| SCHEMBL17666943 | 0.76 | ALDH1A1 (0.53) | POLBHTTNPSR1KDM4EGAA | |
| SCHEMBL17666941 | 0.76 | ALDH1A1 (0.53) | POLBHTTNPSR1KDM4EGAA | |
| SCHEMBL3839168 | 0.72 | PKM (0.50) | KDM4EGAAALDH1A1 | |
| SCHEMBL6002142 | 0.71 | HTT (0.49) | POLBHTTNPSR1KDM4EGAA | |
| SCHEMBL6046931 | 0.69 | MAPT (0.45) | HTTKDM4EGAAL3MBTL1ALDH1A1 | |
| SCHEMBL3635728 | 0.69 | MAPT (0.45) | NPSR1KDM4EGAAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1734939-A1 | ANTI-PARASITIC COMPOUNDS AND METHODS OF THEIR USE | The Regents of The University of California (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005087211-A1 | ANTI-PARASITIC COMPOUNDS AND METHODS OF THEIR USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-09-22 | — | — | WO | disclosed |