Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30729429 | 1.00 | MAPT (0.45) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL11034063 | 0.94 | ADRA2B (0.44) | MAPTMEN1KMT2AKDM4ETDP1 | |
| N,N'-Diphenyl-P-Phenylenediamine SCHEMBL11874052 | 0.93 | ALDH1A1 (0.46) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL1702787 | 0.89 | ADRA2B (0.41) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL176287 | 0.88 | ADRA2C (0.47) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL7757717 | 0.87 | ADRA2B (0.40) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL31530697 | 0.86 | MEN1 (0.48) | MAPTMEN1KMT2AKDM4ETDP1 | |
| Ammonia Solution, Strong SCHEMBL20481810 | 0.84 | MAPT (0.51) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL23491114 | 0.82 | MAPT (0.40) | MAPTMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL3635728 | 0.81 | MAPT (0.45) | MAPTMEN1KMT2AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484472-B | Synthesis method of thioindoline compound | 华中科技大学 | 2020-05-19 | — | — | CN | claimed |
| US-4780546-A | ACID CATALYZED CYCLIZATION OF MALEINAMIC ACIDS | NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) | 1988-10-25 | — | — | US | claimed |
| CN-108484472-B | Synthesis method of thioindoline compound | 华中科技大学 | 2020-05-19 | — | — | CN | disclosed |
| US-10290815-B2 | Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device | IDEMITSU KOSAN CO., LTD. (JP) | 2019-05-14 | — | — | US | disclosed |
| EP-1104687-B1 | Nucleic acid-immobilized substrate | NISSHIN SPINNING (JP) | 2006-04-19 | — | — | EP | disclosed |
| US-6777181-B2 | NUCLEOTIDE SEQUENCE EXTRACTION; MIX PREFERENTIAL NUCLEOTIDE SEQUENCES WITH SUBSTRATE AND SINGLE STRANDED NUCLEOTIDE SEQUENCES, RECOVER HYBIDIZED SEQUENCES AND COLLECT THE HYBRIDIZED SEQUENCES | NISSHINBO INDUSTRIES, INC. (JP) | 2004-08-17 | — | — | US | disclosed |
| US-6498245-B2 | A CARRIER WHICH COMPRISES A BASE MATERIAL AND A COMPOUND HAVING ONE OR MORE ALKYLATING GROUPS AND THE NUCLEIC ACIDS ARE IMMOBILIZED IN MULTI DOT LIKE AREAS ON CARRIER THROUGH INTERMEDIARY OF ALKYLATING GROUPS | NISSHINBO INDUSTRIES, INC. (JP) | 2002-12-24 | — | — | US | disclosed |
| US-20020006666-A1 | Method for separating and collecting nucleic acids | NISSHINBO INDUSTRIES, INC. (JP) | 2002-01-17 | — | — | US | disclosed |
| EP-1130120-A2 | Method for separating and collecting nucleic acids | NISSHINBO INDUSTRIES, INC. (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-20010003649-A1 | Nucleic acid-immobilized substrate | NISSHINBO INDUSTRIES, INC. (JP) | 2001-06-14 | — | — | US | disclosed |
| EP-1104687-A2 | Nucleic acid-immobilized substrate | NISSHINBO INDUSTRIES, INC. (JP) | 2001-06-06 | — | — | EP | disclosed |
| US-3944492-A | Lubricant compositions containing N-substituted naphthylamines as antioxidants | UNIROYAL, INC. (US) | 1976-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10290815-B2 | Composition, compound, material for organic electroluminescence element, ink composition, organic electroluminescence element, and electronic device | EED, BMI1, CD99 | MAPT 1057/4885MEN1 1686/4885KMT2A 461/4885 |
| US-20010003649-A1 | Nucleic acid-immobilized substrate | DNMT1, DNMT3A, DNMT3L | MAPT 3705/4885MEN1 2527/4885KMT2A 257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.