Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11330348 | 0.76 | CA2 (0.67) | CA2PTGS1PTGS2CA1CNR2 | |
| SCHEMBL6000979 | 0.74 | CA2 (0.51) | CA2PTGS1PTGS2CA1SLC22A12 | |
| SCHEMBL4965379 | 0.72 | CA2 (0.49) | CA2PTGS1PTGS2CA1SLC22A12 | |
| SCHEMBL10934176 | 0.72 | PTGS1 (0.64) | CA2PTGS1PTGS2CA1SLC22A12 | |
| SCHEMBL12190934 | 0.69 | LMNA (0.56) | — | |
| SCHEMBL12032534 | 0.68 | ERBB2 (0.58) | ERBB2HSP90AA1HSP90AB1 | |
| SCHEMBL2079574 | 0.68 | CA2 (0.49) | CA2PTGS1PTGS2CA1SLC22A12 | |
| SCHEMBL2080356 | 0.68 | LMNA (0.61) | — | |
| SCHEMBL6001650 | 0.67 | PTGS1 (0.67) | CA2PTGS1PTGS2 | |
| SCHEMBL4720551 | 0.67 | GAA (0.47) | CA2PTGS1PTGS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060281695-A1 | Control of parasites in animals by N-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and N-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281695-A1 | Control of parasites in animals by N-[(phenyloxy)phenyl]-1,1,1-trifluoromethanesulfonamide and N-[(phenylsulfanyl)phenyl]-1,1,1-trifluoromethanesulfonamide derivatives | ELANE, CTRL, PIGO | CA2 3839/4885PTGS1 296/4885PTGS2 1435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.