Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 4/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | BAD | Q92934 | 1/20 | 0.36 |
| ▸ | AGXT | P21549 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL821619 | 0.82 | ALDH1A1 (0.36) | PTPN1NFE2L2 | |
| SCHEMBL4973376 | 0.77 | NFE2L2 (0.54) | NFE2L2 | |
| SCHEMBL27645151 | 0.75 | TRIM24 (0.41) | TRIM24TRIM33MAOAAGXTCA12 | |
| SCHEMBL27767059 | 0.72 | BCL2L1 (0.47) | PTPN1PTPN5TRIM24TRIM33MAOA | |
| SCHEMBL17117419 | 0.71 | MAOA (0.44) | PTPN1PTPN5TRIM24TRIM33MAOA | |
| SCHEMBL5535635 | 0.71 | MAOA (0.44) | PTPN1PTPN5TRIM24TRIM33MAOA | |
| SCHEMBL2843934 | 0.71 | MAOA (0.48) | TRIM24TRIM33MAOABCL2L1BAD | |
| SCHEMBL7535716 | 0.69 | NFE2L2 (0.58) | MAOABCL2L1BADHDAC8NFE2L2 | |
| SCHEMBL530889 | 0.69 | NFE2L2 (0.58) | MAOABCL2L1BADHDAC8NFE2L2 | |
| SCHEMBL1005178 | 0.67 | MAOA (0.44) | TRIM24TRIM33MAOABCL2L1BAD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |