Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | SQOR | Q9Y6N5 | 5/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 2/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001844 | 0.92 | TRPA1 (0.48) | TDO2IDO1SQORTRPA1CYP1A2 | |
| SCHEMBL6001858 | 0.83 | HSD17B1 (0.41) | TDO2SQORTRPA1CYP1A2CYP2C9 | |
| SCHEMBL6001690 | 0.81 | ABCG2 (0.59) | KDM4EALDH1A1LMNAMAPTABCG2 | |
| SCHEMBL6001691 | 0.77 | KDM4E (0.47) | TDO2SQORCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6001423 | 0.77 | ABCG2 (0.64) | TDO2IDO1LMNAMAPTACP1 | |
| SCHEMBL6001924 | 0.76 | KDM4E (0.45) | TDO2IDO1SQORCYP1A2CYP3A4 | |
| SCHEMBL6001386 | 0.76 | TP53 (0.58) | CYP1A2CYP3A4CYP2D6CYP2C19KDM4E | |
| SCHEMBL13443764 | 0.74 | NPC1 (0.59) | SQORKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL6001934 | 0.73 | KDM4E (0.64) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL6001192 | 0.72 | MAPT (0.60) | KDM4EALDH1A1LMNAMAPTABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | REDDY US THERAPEUTICS, INC. | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | HPSE, ENGASE, UGCG | TDO2 1354/4885IDO1 883/4885SQOR 2026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.