Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001858 | 0.88 | HSD17B1 (0.41) | KDM4EMEN1HPGDKMT2AALDH1A1 | |
| SCHEMBL6001844 | 0.78 | TRPA1 (0.48) | KDM4EMEN1HPGDKMT2AALDH1A1 | |
| SCHEMBL6001397 | 0.77 | TDO2 (0.46) | KDM4EHPGDALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL6001386 | 0.76 | TP53 (0.58) | KDM4EMEN1HPGDKMT2AALDH1A1 | |
| SCHEMBL8652143 | 0.72 | HSP90AA1 (0.47) | HSD17B2SCN9A | |
| SCHEMBL6001924 | 0.71 | KDM4E (0.45) | KDM4EMEN1HPGDKMT2AALDH1A1 | |
| SCHEMBL7258823 | 0.71 | CYP19A1 (0.47) | KDM4EMEN1HPGDKMT2AALDH1A1 | |
| SCHEMBL5999859 | 0.68 | LMNA (0.51) | KDM4EHPGDALDH1A1DHODHMAPT | |
| SCHEMBL30497936 | 0.66 | ADORA2A (0.50) | KDM4EALDH1A1DHODHMAPTSQOR | |
| SCHEMBL21644727 | 0.66 | ADORA2A (0.50) | KDM4EALDH1A1DHODHMAPTSQOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | REDDY US THERAPEUTICS, INC. | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | HPSE, ENGASE, UGCG | KDM4E 2893/4885MEN1 2168/4885HPGD 189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.