Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 10/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.59 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001690 | 0.92 | ABCG2 (0.59) | MAPTTP53SMN1; SMN2ABCG2ABCB1 | |
| SCHEMBL6001844 | 0.80 | TRPA1 (0.48) | MAPTTP53SMN1; SMN2ABCG2ABCB1 | |
| SCHEMBL6001934 | 0.80 | KDM4E (0.64) | MAPTTP53SMN1; SMN2ABCG2ABCB1 | |
| SCHEMBL6001975 | 0.78 | ABCG2 (0.88) | MAPTTP53SMN1; SMN2ABCG2ABCB1 | |
| SCHEMBL6001935 | 0.77 | LMNA (0.55) | MAPTTP53SMN1; SMN2ABCG2KDM4E | |
| SCHEMBL6001437 | 0.77 | KDM4E (0.71) | MAPTABCG2ABCB1ABCC1KDM4E | |
| SCHEMBL16404295 | 0.74 | ABCG2 (1.00) | MAPTTP53SMN1; SMN2ABCG2ABCB1 | |
| SCHEMBL16404335 | 0.74 | ABCG2 (0.74) | MAPTABCG2KDM4ELMNAMAPK1 | |
| SCHEMBL15347452 | 0.74 | MAPK1 (0.84) | MAPTABCG2KDM4ELMNAMAPK1 | |
| SCHEMBL23743253 | 0.74 | MAPT (0.72) | MAPTABCG2KDM4ELMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | REDDY US THERAPEUTICS, INC. | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | HPSE, ENGASE, UGCG | MAPT 4070/4885TP53 886/4885SMN1; SMN2 3583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.