SCHEMBL600144

SCHEMBL600144

Cc1ccc(C(=O)Cl)cn1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.60
HDAC6 Q9UBN7 1/20 0.60
KDM4E B2RXH2 2/20 0.49
NAPRT Q6XQN6 1/20 0.45
KMT2A Q03164 4/20 0.44
KCNQ3 O43525 1/20 0.41
KCNQ2 O43526 1/20 0.41
MAPT P10636 1/20 0.41
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
PRKAB2 O43741 1/20 0.41
PRKAG1 P54619 1/20 0.41
PRKAA2 P54646 1/20 0.41
PRKAA1 Q13131 1/20 0.41
PRKAG3 Q9UGI9 1/20 0.41
PRKAG2 Q9UGJ0 1/20 0.41
PRKAB1 Q9Y478 1/20 0.41
POLB P06746 1/20 0.40
NPC1 O15118 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3891479 0.98 HDAC1 (0.58) HDAC1HDAC6KDM4ENAPRTKMT2A
SCHEMBL4400941 0.82 HDAC1 (0.64) HDAC1HDAC6KDM4EKMT2AKCNQ3
SCHEMBL8000244 0.80 HDAC1 (0.52) HDAC1HDAC6KDM4ENAPRTKMT2A
SCHEMBL575041 0.80 HDAC1 (0.62) HDAC1HDAC6KDM4EKMT2AKCNQ3
SCHEMBL181465 0.80 HDAC1 (0.62) HDAC1HDAC6KDM4ENAPRTMAPT
SCHEMBL31290288 0.80 HDAC1 (0.62) HDAC1HDAC6KDM4EKMT2AKCNQ3
SCHEMBL30544993 0.80 HDAC1 (0.62) HDAC1HDAC6KDM4ENAPRTMAPT
SCHEMBL2488844 0.78 HDAC1 (0.60) HDAC1HDAC6KDM4EKMT2AKCNQ3
SCHEMBL351856 0.78 NNMT (0.61) HDAC1HDAC6KDM4ESMN1; SMN2LMNA
SCHEMBL9504571 0.78 HDAC1 (0.60) HDAC1HDAC6KDM4ENAPRTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2350 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116284203-B Tanshinone IIA C-1 position esterified derivative and preparation method and application thereof 郑州大学 2025-06-10 CN claimed
CN-119874597-A Preparation method of medical intermediate 百泰生物药业有限公司 2025-04-25 CN claimed
CN-119462646-A Substituted tetrahydro-beta-carboline derivative, synthesis method and application thereof 江苏科技大学 2025-02-18 CN claimed
CN-116410106-B Benzamide HBV capsid protein inhibitor and preparation method and application thereof 山东第二医科大学 2024-12-06 CN claimed
CN-114507159-B Preparation method of 4- [3 (E) -pentene-1-yl ] benzoate liquid crystal monomer 中节能万润股份有限公司 2024-05-03 CN claimed
CN-117024298-A Tertiary amide compound containing naphthyl and its preparation method and application 北京中医药大学 2023-11-10 CN claimed
CN-116941616-A Application of narinone derivative in preparing medicine for preventing and treating plant pathogenic fungi 贵州省天然产物研究中心 2023-10-27 CN claimed
CN-116535649-A Aromatic sulfone polymer and polymerization method and application thereof 珠海万通特种工程塑料有限公司 2023-08-04 CN claimed
CN-116410106-A Benzamide HBV capsid protein inhibitor and preparation method and application thereof 潍坊医学院 2023-07-11 CN claimed
CN-116284203-A Tanshinone IIA C-1 position esterified derivative and preparation method and application thereof 郑州大学 2023-06-23 CN claimed
US-20100022794-A1 Method for producing acyl peroxides UNITED INITIATORS GMBH (DE) 2010-01-28 US claimed
WO-2009072139-A1 PROCESS FOR PRODUCING 2-[1-METHYL-5-(4-METHYLBENZOYL)- PYRROL-2- YL]ACETIC ACID OR SALT THEREOF MATRIX LABORATORIES LIMITED (IN) 2009-06-11 WO claimed
US-20090105440-A1 Filler for Optical Isomer Separation NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2009-04-23 US claimed
EP-2028487-A1 FILLER FOR OPTICAL ISOMER SEPARATION National University Corporation Nagoya University (JP) 2009-02-25 EP claimed
EP-2001957-A1 HEAT-CURABLE SILICONE RUBBER COMPOSITION AND A CURED BODY THEREOF Dow Corning Toray Co., Ltd. (JP) 2008-12-17 EP claimed
WO-2007119669-A1 HEAT-CURABLE SILICONE RUBBER COMPOSITION AND A CURED BODY THEREOF DOW CORNING TORAY CO., LTD. (JP) 2007-10-25 WO claimed
US-6369246-B2 ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANTITUMOR AGENTS DR. KEITH CHAN, GLOBOASIA, LLC 2002-04-09 US claimed
US-20010018539-A1 Synthesis and pharmaceuticals of novel 9-substituted-1, 5-dichloroanthracene analogs CHAN, KEITH 2001-08-30 US claimed
WO-2000061536-A2 SYNTHESIS AND PHARMACEUTICALS OF NOVEL 9-SUBSTITUTED-1,5-DICHLOROANTHRACENE ANALOGS GLOBOASIA, L.L.C. (US) 2000-10-19 WO claimed
EP-0440329-A1 S-substituted carbonyl substituted betathioacrylamide biocides and fungicides ROHM AND HAAS COMPANY (US) 1991-08-07 EP claimed