Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948362 | 0.82 | HDAC1 (0.52) | HDAC1HDAC6KDM4EADRA2AADRA2B | |
| SCHEMBL1436032 | 0.80 | HDAC1 (0.50) | HDAC1HDAC6KDM4EADRA2AADRA2B | |
| SCHEMBL11344489 | 0.80 | HDAC1 (0.50) | HDAC1HDAC6KDM4EADRA2AADRA2B | |
| SCHEMBL600144 | 0.80 | HDAC1 (0.60) | HDAC1HDAC6KDM4EKMT2ANAPRT | |
| Hydrochloric Acid SCHEMBL3891479 | 0.78 | HDAC1 (0.58) | HDAC1HDAC6KDM4EADRA2AADRA2B | |
| SCHEMBL4491812 | 0.77 | HDAC1 (0.47) | HDAC1HDAC6KDM4EADRA2AADRA2B | |
| SCHEMBL4491815 | 0.77 | HDAC1 (0.47) | HDAC1HDAC6KDM4EADRA2AADRA2B | |
| SCHEMBL4400941 | 0.74 | HDAC1 (0.64) | HDAC1HDAC6KDM4EKMT2AKCNQ3 | |
| Potassium Ion SCHEMBL7741543 | 0.74 | HDAC1 (0.58) | HDAC1HDAC6KDM4EKMT2AKCNQ3 | |
| SCHEMBL3394733 | 0.74 | HDAC1 (0.58) | HDAC1HDAC6KDM4EKMT2AKCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294536-B1 | CONTROL OF PROTOZOA AND REDUCTION IN THE INCIDENCE OF ASSOCIATED DISEASES AND DEATH AND CONSEQUENT IMPROVEMENT IN RETARDED GROWTH AND GENERAL CONDITION AND PREVENTING DECREASE GROWTH AND GENERAL CONDITION | TAKEDA SCHERING-PLOUGH ANIMAL HEALTH K.K. (JP) | 2001-09-25 | — | — | US | disclosed |
| WO-1999011634-A1 | TRIAZINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-11 | — | — | WO | disclosed |
| EP-0163855-B1 | NITROMETHYLENE DERIVATIVES, INTERMEDIATES, AND PROCESS FOR THEIR PREPARATION AS INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-06-21 | — | — | EP | disclosed |
| US-4812571-A | NITROMETHYLENE COMPOUNDS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-03-14 | — | — | US | disclosed |
| US-4774247-A | Nitromethylene derivative insecticides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-09-27 | — | — | US | disclosed |
| US-4678795-A | 1-pyridylmethyl-2-nitromethylene-1,3-diazacycloalkane insecticides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1987-07-07 | — | — | US | disclosed |
| EP-0163855-A1 | Nitromethylene derivatives, intermediates, and process for their preparation as insecticides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-12-11 | — | — | EP | disclosed |