Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CCR9 | P51686 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.42 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.42 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31290288 | 1.00 | HDAC1 (0.62) | HDAC1HDAC6KDM4EKCNJ1KMT2A | |
| Hydrochloric Acid SCHEMBL2750908 | 0.98 | HDAC1 (0.60) | HDAC1HDAC6KDM4EKCNJ1KMT2A | |
| Glyoxylate SCHEMBL28763022 | 0.90 | HDAC1 (0.53) | HDAC1HDAC6KDM4EKCNJ1KMT2A | |
| SCHEMBL17750025 | 0.85 | HDAC1 (0.56) | HDAC1HDAC6KDM4EKMT2AMAPT | |
| SCHEMBL4400941 | 0.84 | HDAC1 (0.64) | HDAC1HDAC6KDM4EKMT2ACCR9 | |
| SCHEMBL1138580 | 0.84 | HSD17B1 (0.53) | HDAC1HDAC6KDM4EMAPTLMNA | |
| SCHEMBL30544993 | 0.82 | HDAC1 (0.62) | HDAC1HDAC6KDM4EMAPTALDH1A1 | |
| SCHEMBL181465 | 0.82 | HDAC1 (0.62) | HDAC1HDAC6KDM4EMAPTALDH1A1 | |
| SCHEMBL351856 | 0.80 | NNMT (0.61) | HDAC1HDAC6KDM4ELMNAL3MBTL1 | |
| SCHEMBL600144 | 0.80 | HDAC1 (0.60) | HDAC1HDAC6KDM4EKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 524 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4581071-A1 | METHOD FOR PRODUCING A MATERIAL FOR A MEMBRANE, MATERIAL, MEMBRANE AND USE OF A MEMBRANE | Forschungszentrum Jülich GmbH (DE) | 2025-07-09 | — | — | EP | claimed |
| CN-119375400-A | Sample pretreatment method for detecting CD38 enzyme activity in whole blood sample and method for detecting blood CD38 enzyme activity by high performance liquid chromatography | 北京医院 | 2025-01-28 | — | — | CN | claimed |
| CN-119019363-A | Synthesis method of 6-methyl nicotine | 东莞市鸿馥生物科技有限公司 | 2024-11-26 | — | — | CN | claimed |
| WO-2024046712-A1 | METHOD FOR PRODUCING A MATERIAL FOR A MEMBRANE, MATERIAL, MEMBRANE AND USE OF A MEMBRANE | Forschungszentrum Jülich GmbH (DE) | 2024-03-07 | — | — | WO | claimed |
| CN-108456162-A | Preparation process of 2-methyl-5-acetylpyridine | 海门市新港医药科技有限公司 | 2018-08-28 | — | — | CN | claimed |
| CN-103145707-B | The preparation method of hydrogenated pyridine [4,3-b] Benzazole compounds | Institute of Toxicology and Drugs, Chinese Academy of Military Medical Sciences (CN) | 2016-05-25 | — | — | CN | claimed |
| EP-2757095-B1 | Very efficient process for preparing an intermediate of Etoricoxib | ITALIANA SINT SPA (IT) | 2015-03-18 | — | — | EP | claimed |
| US-20140206882-A1 | VERY EFFICIENT PROCESS FOR PREPARING AN INTERMEDIATE OF ETORICOXIB | F.I.S. - FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2014-07-24 | — | — | US | claimed |
| EP-2757095-A1 | Very efficient process for preparing an intermediate of Etoricoxib | F.I.S.- Fabbrica Italiana Sintetici S.p.A. (IT) | 2014-07-23 | — | — | EP | claimed |
| US-8765962-B1 | Very efficient process for preparing an intermediate of etoricoxib | F.I.S.—Fabrica Italiana Sintetici S.p.A. (IT) | 2014-07-01 | — | — | US | claimed |
| EP-2497767-A1 | Improved process for preparing 1-(6-methylpyridin-3-yl)-2-[4-(methylsulfonyl)phenyl]ethanone, an intermediate of etoricoxib | F.I.S. Fabbrica Italiana Sintetici S.p.A. (IT) | 2012-09-12 | — | — | EP | claimed |
| US-20120122914-A1 | Sustained-release composition containing tetrahydropyrido[4,3-b]indole derivatives and preparation of the derivatives | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCE P.L.A.CHINA (CN) | 2012-05-17 | — | — | US | claimed |
| CN-102395369-A | Sustained-release composition containing tetrahydropyridine [4,3-b ] indole derivative and preparation method of derivative | INST PHARM & TOXICOLOGY AMMS | 2012-03-28 | — | — | CN | claimed |
| EP-2417973-A1 | SUSTAINED RELEASE COMPOSITION CONTAINING TETRAHYDROPYRIDO Ý4, 3-b¨INDOLE DERIVATIVE AND PREPARATION METHOD OF DERIVATIVE | Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. (CN) | 2012-02-15 | — | — | EP | claimed |
| EP-0269407-B1 | Insoluble complex oxidation catalysts | REILLY IND INC (US) | 1994-09-14 | — | — | EP | claimed |
| EP-0159769-B1 | ELECTROCHEMICAL OXIDATION OF PYRIDINE BASES | REILLY INDUSTRIES, INC. (US) | 1991-03-27 | — | — | EP | claimed |
| EP-0269407-A1 | Insoluble complex oxidation catalysts | REILLY INDUSTRIES, INC. (US) | 1988-06-01 | — | — | EP | claimed |
| EP-0159769-A1 | Electrochemical oxidation of pyridine bases | REILLY INDUSTRIES, INC. (US) | 1985-10-30 | — | — | EP | claimed |
| US-4482439-A | Electrochemical oxidation of pyridine bases | REILLY TAR & CHEMICAL CORP. (US) | 1984-11-13 | — | — | US | claimed |
| US-4374051-A | ISOPROPENYL- OR ACETYL SUBSTITUTED PYRIDINE DERIVATIVES; REGENERATION OF ESSENTIAL OILS; FLAVORS | FIRMENICH SA (CH) | 1983-02-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140206882-A1 | VERY EFFICIENT PROCESS FOR PREPARING AN INTERMEDIATE OF ETORICOXIB | PTGES, PTGES2, PTGS1 | HDAC1 4507/4885HDAC6 4307/4885KDM4E 257/4885 |
| US-20120122914-A1 | Sustained-release composition containing tetrahydropyrido[4,3-b]indole derivatives and preparation of the derivatives | HTT, HTR5A, HTR3B | HDAC1 1435/4885HDAC6 1697/4885KDM4E 895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.