Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.47 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001834 | 0.82 | KDM4E (0.62) | LMNARAB9ATP53SMN1; SMN2NPC1 | |
| SCHEMBL6001405 | 0.81 | SMN1; SMN2 (0.57) | GBA1LMNARAB9ATP53SMN1; SMN2 | |
| SCHEMBL6001935 | 0.79 | LMNA (0.55) | LMNARAB9ATP53SMN1; SMN2NPC1 | |
| SCHEMBL6001380 | 0.76 | PDE5A (0.67) | GBA1LMNATP53ALDH1A1MEN1 | |
| SCHEMBL6001165 | 0.75 | KDM4E (0.54) | GBA1LMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL30969595 | 0.73 | HPGD (0.57) | LMNARAB9ATP53SMN1; SMN2NPC1 | |
| SCHEMBL5999882 | 0.68 | LMNA (0.59) | LMNARAB9ATP53SMN1; SMN2NPC1 | |
| SCHEMBL6001908 | 0.67 | PTGS2 (0.49) | LMNARAB9ATP53SMN1; SMN2NPC1 | |
| SCHEMBL38652052 | 0.67 | KDM4E (0.47) | GBA1LMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6001899 | 0.67 | MAPT (0.55) | LMNARAB9ATP53SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | REDDY US THERAPEUTICS, INC. | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | HPSE, ENGASE, UGCG | GBA1 38/4885LMNA 706/4885RAB9A 4177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.