Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 6/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | MC5R | P33032 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1272400 | 0.85 | PTGS1 (0.49) | PTGS1PTGS2CYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL6736271 | 0.81 | CYP1A2 (0.60) | PTGS1PTGS2CYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL6001878 | 0.79 | PTGS1 (0.51) | PTGS1PTGS2CYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL347497 | 0.78 | SMN1; SMN2 (0.54) | PTGS1PTGS2CYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL20733630 | 0.78 | PTGS1 (0.54) | PTGS1PTGS2CYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL13283703 | 0.78 | PTGS1 (0.50) | PTGS1PTGS2CYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL11471037 | 0.76 | CYP1A2 (0.73) | PTGS1PTGS2CYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL10670085 | 0.76 | SMN1; SMN2 (0.53) | PTGS1PTGS2CYP1A2CYP2D6SMN1; SMN2 | |
| Hydrogen Sulfide SCHEMBL28224514 | 0.76 | SMN1; SMN2 (0.53) | PTGS1PTGS2CYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL10670562 | 0.76 | SMN1; SMN2 (0.53) | PTGS1PTGS2CYP1A2CYP2D6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230321050-A1 | Heterocyclic Compounds and Uses Thereof | MILLENNIUM PHARMACEUTICALS, INC. | 2023-10-12 | — | — | US | disclosed |
| US-20230174526-A1 | BENZOTHIAZOLYL BIARYL COMPOUND, AND PREPARATION METHOD AND USE | SHANGHAI RINGENE THERAPEUTICS CO. LTD (CN) | 2023-06-08 | — | — | US | disclosed |
| EP-4144732-A1 | BENZOTHIAZOLYL BIARYL COMPOUND, AND PREPARATION METHOD AND USE | Shanghai Ringene BioPharma Co., Ltd. (CN) | 2023-03-08 | — | — | EP | disclosed |
| US-11547697-B2 | Heterocyclic compounds and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2023-01-10 | — | — | US | disclosed |
| US-20190350906-A1 | Heterocyclic Compounds and Uses Thereof | INTELLIKINE, LLC | 2019-11-21 | — | — | US | disclosed |
| EP-2467141-B1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | INTELLIKINE LLC (US) | 2018-10-31 | — | — | EP | disclosed |
| US-20180042902-A1 | Heterocyclic Compounds and Uses Thereof | INTELLIKINE, LLC | 2018-02-15 | — | — | US | disclosed |
| EP-2678016-B1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | INTELLIKINE LLC (US) | 2016-08-10 | — | — | EP | disclosed |
| US-20150320727-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | INTELLIKINE, LLC | 2015-11-12 | — | — | US | disclosed |
| US-9127000-B2 | Heterocyclic compounds and uses thereof | Intellikine, LLC. (US) | 2015-09-08 | — | — | US | disclosed |
| US-20100055800-A1 | Compositions for Chemiluminescent Detection of Hydrogen Peroxide | LUMIGEN, INC. (US) | 2010-03-04 | — | — | US | disclosed |
| US-20080261318-A1 | Signalling Compounds For Use In Methods Of Detecting Hydrogen Peroxide | LUMIGEN, INC. (US) | 2008-10-23 | — | — | US | disclosed |
| US-7390670-B2 | Signalling compounds and methods for detecting hydrogen peroxide | LUMIGEN, INC. (US) | 2008-06-24 | — | — | US | disclosed |
| EP-1594855-A4 | SIGNALLING COMPOUNDS FOR USE IN METHODS OF DETECTING HYDROGEN PEROXIDE | LUMIGEN INC (US) | 2008-04-16 | — | — | EP | disclosed |
| EP-1594855-A2 | SIGNALLING COMPOUNDS FOR USE IN METHODS OF DETECTING HYDROGEN PEROXIDE | LUMIGEN, INC. (US) | 2005-11-16 | — | — | EP | disclosed |
| US-6919463-B2 | Signalling compounds for use in methods of detecting hydrogen peroxide | LUMIGEN, INC. (US) | 2005-07-19 | — | — | US | disclosed |
| WO-2004074810-A2 | SIGNALLING COMPOUNDS FOR USE IN METHODS OF DETECTING HYDROGEN PEROXIDE | LUMIGEN INC. (US) | 2004-09-02 | — | — | WO | disclosed |
| US-20040171098-A1 | Signalling compounds for use in methods of detecting hydrogen peroxide | LUMIGEN INC. | 2004-09-02 | — | — | US | disclosed |
| US-20040166539-A1 | Signalling compounds and methods for detecting hydrogen peroxide | LUMIGEN, INC. | 2004-08-26 | — | — | US | disclosed |
| US-6100405-A | Benzothiazole-containing two-photon chromophores exhibiting strong frequency upconversion | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2000-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230321050-A1 | Heterocyclic Compounds and Uses Thereof | PIK3CA, PIK3CD, PIK3CB | PTGS1 1620/4885PTGS2 1740/4885CYP1A2 1496/4885 |
| US-20230174526-A1 | BENZOTHIAZOLYL BIARYL COMPOUND, AND PREPARATION METHOD AND USE | KRAS, NRAS, HRAS | PTGS1 3307/4885PTGS2 3311/4885CYP1A2 634/4885 |
| US-11547697-B2 | Heterocyclic compounds and uses thereof | PIK3CA, PIK3CD, PIK3CB | PTGS1 1620/4885PTGS2 1740/4885CYP1A2 1496/4885 |
| US-20150320727-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | PIK3CA, PIK3CD, PIK3CB | PTGS1 1620/4885PTGS2 1740/4885CYP1A2 1496/4885 |
| US-20180042902-A1 | Heterocyclic Compounds and Uses Thereof | PIK3CA, PIK3CD, PIK3CB | PTGS1 1620/4885PTGS2 1740/4885CYP1A2 1496/4885 |
| US-20190350906-A1 | Heterocyclic Compounds and Uses Thereof | PIK3CA, PIK3CD, PIK3CB | PTGS1 1620/4885PTGS2 1740/4885CYP1A2 1496/4885 |
| US-20040171098-A1 | Signalling compounds for use in methods of detecting hydrogen peroxide | LPO, HAO2, HAO1 | PTGS1 592/4885PTGS2 721/4885CYP1A2 530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.