Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | TFEB | P19484 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7625428 | 1.00 | ALOX5 (0.53) | ALOX5NFE2L2PPARGS1PR1PTGER4 | |
| SCHEMBL6001910 | 0.84 | PPARG (0.53) | PPARGS1PR1CYSLTR2CYSLTR1PDE4A | |
| SCHEMBL6001877 | 0.80 | LTB4R (0.42) | ALOX5PPARGS1PR1PTGER4PTGER3 | |
| SCHEMBL9219599 | 0.79 | MAPT (0.65) | ALOX5HDAC1HDAC2FAAHMAPT | |
| SCHEMBL9404041 | 0.79 | MAPT (0.65) | ALOX5HDAC1HDAC2FAAHMAPT | |
| SCHEMBL9764517 | 0.79 | MAPT (0.65) | ALOX5HDAC1HDAC2FAAHMAPT | |
| SCHEMBL8662111 | 0.79 | MAPT (0.65) | ALOX5HDAC1HDAC2FAAHMAPT | |
| SCHEMBL29048467 | 0.79 | MAPT (0.65) | ALOX5HDAC1HDAC2FAAHMAPT | |
| SCHEMBL20717644 | 0.79 | MAPT (0.65) | ALOX5HDAC1HDAC2FAAHMAPT | |
| SCHEMBL9404082 | 0.79 | MAPT (0.65) | ALOX5HDAC1HDAC2FAAHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1655280-A1 | Dicarboxylic acid derivates with pharmaceutical properties | Bayer HealthCare AG (DE) | 2006-05-10 | — | — | EP | disclosed |
| EP-1216222-A2 | NOVEL DERIVATIVES OF DICARBOXYLIC ACID HAVING PHARMACEUTICAL PROPERTIES | Bayer Aktiengesellschaft (DE) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001019776-A2 | NOVEL DERIVATIVES OF DICARBOXYLIC ACID HAVING PHARMACEUTICAL PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-03-22 | — | — | WO | disclosed |