Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6000368 | 0.88 | PPARG (0.54) | PPARGPPARALTB4RLTB4R2CYSLTR2 | |
| SCHEMBL9122597 | 0.80 | LTB4R (0.54) | PPARGPPARALTB4RLTB4R2PPARD | |
| SCHEMBL6001865 | 0.79 | PPARG (0.43) | PPARGPPARAPTGESALOX5PPARD | |
| SCHEMBL6280259 | 0.78 | PPARG (0.42) | PPARGPPARALTB4RLTB4R2CYSLTR2 | |
| SCHEMBL6001910 | 0.77 | PPARG (0.53) | PPARGPPARACYSLTR2CYSLTR1FAAH | |
| SCHEMBL9404041 | 0.76 | MAPT (0.65) | ALOX5FAAHCES1 | |
| SCHEMBL9219599 | 0.76 | MAPT (0.65) | ALOX5FAAHCES1 | |
| SCHEMBL8662111 | 0.76 | MAPT (0.65) | ALOX5FAAHCES1 | |
| SCHEMBL20717644 | 0.76 | MAPT (0.65) | ALOX5FAAHCES1 | |
| SCHEMBL9764517 | 0.76 | MAPT (0.65) | ALOX5FAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1655280-A1 | Dicarboxylic acid derivates with pharmaceutical properties | Bayer HealthCare AG (DE) | 2006-05-10 | — | — | EP | disclosed |