Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 5/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001865 | 0.85 | PPARG (0.43) | PPARGPPARAPTGESALOX5FAAH | |
| SCHEMBL6000368 | 0.78 | PPARG (0.54) | PPARGPPARAPTGESALOX5FAAH | |
| SCHEMBL6001980 | 0.78 | PPARG (0.51) | PPARGPPARAPTGESALOX5FAAH | |
| SCHEMBL13443503 | 0.76 | PPARD (0.44) | PPARGPPARALTB4RLTB4R2HPGD | |
| SCHEMBL13009527 | 0.72 | FAAH (0.42) | FAAH | |
| SCHEMBL13009622 | 0.72 | FAAH (0.42) | FAAH | |
| SCHEMBL13443505 | 0.71 | L3MBTL1 (0.47) | — | |
| SCHEMBL13009623 | 0.71 | PTGER1 (0.42) | FAAH | |
| SCHEMBL9122597 | 0.71 | LTB4R (0.54) | PPARGPPARALTB4RLTB4R2 | |
| SCHEMBL13443506 | 0.70 | L3MBTL1 (0.46) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6864287-B1 | Derivatives of dicarboxylic acid having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-08 | — | — | US | disclosed |