Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | CDC42 | P60953 | 1/20 | 0.40 |
| ▸ | RAC1 | P63000 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1368738 | 0.84 | TDP1 (0.44) | KDM4EALDH1A1CYP1A2EDNRBEDNRA | |
| SCHEMBL1369990 | 0.82 | PPARA (0.54) | KDM4EALDH1A1CYP1A2EDNRBEDNRA | |
| SCHEMBL1371347 | 0.82 | PKM (0.50) | KDM4EALDH1A1EDNRBEDNRAHPGD | |
| SCHEMBL1371128 | 0.80 | PTPN1 (0.43) | AKR1C3AKR1C2PTGS2CYP1A2CYP2D6 | |
| SCHEMBL1369029 | 0.80 | ABCB11 (0.41) | AKR1C3AKR1C2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL1368634 | 0.79 | FFAR1 (0.45) | CYP1A2CYP2C19 | |
| SCHEMBL6002057 | 0.78 | TBXA2R (0.40) | KDM4EPOLBALDH1A1HPGDMAPT | |
| SCHEMBL3979786 | 0.74 | LDHA (0.59) | KDM4EPOLBALDH1A1CYP1A2TSHR | |
| SCHEMBL2283360 | 0.73 | KMT2A (0.43) | KDM4ECYP1A2EDNRBEDNRACYP2C19 | |
| SCHEMBL1371122 | 0.73 | FFAR1 (0.42) | ALDH1A1EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060211765-A1 | Novel compounds | ASTRAZENECA AB (SE) | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211765-A1 | Novel compounds | ADRA2C, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HCAR2 | AKR1C3 333/4885AKR1C2 375/4885KDM4E 1696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.