Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27907606 | 0.84 | PNMT (0.38) | THRATHRBPTGS2TSHRKDM4E | |
| SCHEMBL28929275 | 0.82 | PTGS2 (0.35) | L3MBTL1THRATHRBPTGS2TSHR | |
| SCHEMBL27920391 | 0.81 | L3MBTL1 (0.54) | L3MBTL1MAPTNPSR1THRATHRB | |
| SCHEMBL28008692 | 0.79 | PTGS2 (0.42) | L3MBTL1MAPTNPSR1THRATHRB | |
| SCHEMBL29587376 | 0.79 | L3MBTL1 (0.50) | L3MBTL1MAPTNPSR1THRATHRB | |
| SCHEMBL47950 | 0.79 | L3MBTL1 (0.50) | L3MBTL1MAPTNPSR1THRATHRB | |
| SCHEMBL7064536 | 0.79 | L3MBTL1 (0.50) | L3MBTL1MAPTNPSR1THRATHRB | |
| SCHEMBL28129455 | 0.78 | TDP1 (0.44) | L3MBTL1MAPTNPSR1THRATHRB | |
| SCHEMBL28118337 | 0.78 | CA1 (0.50) | L3MBTL1MAPTTSHRHSD17B10ATM | |
| SCHEMBL30850062 | 0.77 | PTGS2 (0.55) | L3MBTL1MAPTNPSR1PTGS2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060252906-A1 | Method of synthesis of polyarylenes and the polyarylenes made by such method | GODSCHALX JAMES P | 2006-11-09 | — | — | US | disclosed |
| WO-2004073824-A2 | METHOD OF SYNTHESIS OF POLYARYLENES AND THE POLYARYLENES MADE BY SUCH METHOD | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-09-02 | — | — | WO | disclosed |
| EP-0489877-B1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 2-AMINO-6-PHENYL-4H-PYRAN-4-ONES | UPJOHN CO (US) | 1995-09-20 | — | — | EP | disclosed |
| US-5302613-A | Antiatheroscleroic and antithrombotic 2-amino-6-phenyl-4H-pyran-4-ones | THE UPJOHN COMPANY (US) | 1994-04-12 | — | — | US | disclosed |
| US-5252735-A | Antiatherosclerotic and antithrombotic 2-amino-6-phenyl-4H-pyran-4-ones | THE UPJOHN COMPANY (US) | 1993-10-12 | — | — | US | disclosed |