Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10456930 | 1.00 | EPHX1 (0.32) | EPHX1HIF1AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11920241 | 1.00 | EPHX1 (0.32) | EPHX1HIF1AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL12393331 | 1.00 | EPHX1 (0.32) | EPHX1HIF1AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL59959 | 1.00 | — | — | |
| SCHEMBL14027929 | 1.00 | EPHX1 (0.32) | EPHX1HIF1AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL10456932 | 1.00 | EPHX1 (0.32) | EPHX1HIF1AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7082443 | 1.00 | EPHX1 (0.32) | EPHX1HIF1AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4624851 | 1.00 | EPHX1 (0.32) | EPHX1HIF1AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL12635200 | 1.00 | EPHX1 (0.32) | EPHX1HIF1AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30570889 | 1.00 | EPHX1 (0.32) | EPHX1HIF1AALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874625-A | Process to hydrogenate organic nitriles to primary amines | HENKEL CORPORATION (US) | 1999-02-23 | — | — | US | claimed |
| WO-1998019991-A1 | IMPROVED PROCESS TO HYDROGENATE ORGANIC NITRILES TO PRIMARY AMINES | HENKEL CORPORATION (US) | 1998-05-14 | — | — | WO | claimed |
| US-4650516-A | PLANT SAFENING AGENTS | STAUFFER CHEMICAL CO. (US) | 1987-03-17 | — | — | US | claimed |
| US-4288384-A | N-Cyanoalkyl haloacetamides herbicidal antidotes | STAUFFER CHEMICAL COMPANY (US) | 1981-09-08 | — | — | US | claimed |
| US-20240336711-A1 | REAGENTS AND METHODS FOR ALIPHATIC CARBON-HYDROGEN BOND FUNCTIONALIZATION | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2024-10-10 | — | — | US | disclosed |
| WO-2022241129-A1 | REAGENTS AND METHODS FOR ALIPHATIC CARBON—HYDROGEN BOND FUNCTIONALIZATION | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2022-11-17 | — | — | WO | disclosed |
| US-10597356-B2 | Process for the catalytic reversible alkene-nitrile interconversion | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2020-03-24 | — | — | US | disclosed |
| EP-3184171-B1 | PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2019-03-20 | — | — | EP | disclosed |
| US-20190031602-A1 | PROCESS FOR THE CATALYTIC REVERSIBLE ALKENE-NITRILE INTERCONVERSION | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2019-01-31 | — | — | US | disclosed |
| US-10144752-B2 | Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2018-12-04 | — | — | US | disclosed |
| US-20170305945-A1 | Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2017-10-26 | — | — | US | disclosed |
| US-9764038-B2 | Enzymatic conjugation of antibodies | INNATE PHARMA (FR) | 2017-09-19 | — | — | US | disclosed |
| US-4955901-A | HYDROPHILIC SURFACE TREATMENT | CANON KABUSHIKI KAISHA (JP) | 1990-09-11 | — | — | US | disclosed |
| US-4948910-A | HEATING, PRESSURIZATION AND CONTACTING WITH OXYGEN TO FORM AN UNSATURATED ALIPHATIC NITRILE | DOW CHEMICAL COMPANY, THE | 1990-08-14 | — | — | US | disclosed |
| US-4739120-A | RHODIUM CATALYST, BASIC SOLUTION OR IMMISCIBLE ORGANIC SOLVENT AND WATER | THE DOW CHEMICAL COMPANY (US) | 1988-04-19 | — | — | US | disclosed |
| US-4571435-A | SUSTAINED RELEASE | TENNESSEE VALLEY AUTHORITY (US) | 1986-02-18 | — | — | US | disclosed |
| US-4485225-A | USING RADICAL INITIATOR; GELATION INHIBITION | KURARAY CO., LTD. (JP) | 1984-11-27 | — | — | US | disclosed |
| US-4379939-A | Preparation of nitrogen fertilizers from oxalate esters prepared by the oxidative carbonylation of alcohols over noble metal catalysts utilizing regenerable 2,5-cyclohexadiene-1,4-dione oxidants | TENNESSEE VALLEY AUTHORITY (US) | 1983-04-12 | — | — | US | disclosed |
| US-4318900-A | STIMULANTS | WILKINSON SWORD LIMITED (GB) | 1982-03-09 | — | — | US | disclosed |
| US-4248859-A | USED IN EDIBLE AND TOPICAL PREPARATIONS | WILKINSON SWORD LIMITED (GB) | 1981-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240336711-A1 | REAGENTS AND METHODS FOR ALIPHATIC CARBON-HYDROGEN BOND FUNCTIONALIZATION | NCF1, SHROOM3, NPM1 | EPHX1 3829/4885HIF1A 1356/4885ALDH1A1 2010/4885 |
| US-20190031602-A1 | PROCESS FOR THE CATALYTIC REVERSIBLE ALKENE-NITRILE INTERCONVERSION | HCN2, HCN1, HCN4 | EPHX1 1075/4885HIF1A 633/4885ALDH1A1 939/4885 |
| US-10144752-B2 | Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins | NIT2, NCLN, NPM1 | EPHX1 4474/4885HIF1A 4859/4885ALDH1A1 4849/4885 |
| US-10597356-B2 | Process for the catalytic reversible alkene-nitrile interconversion | HCN2, HCN1, HCN4 | EPHX1 1075/4885HIF1A 633/4885ALDH1A1 939/4885 |
| US-20170305945-A1 | Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins | NIT2, NCLN, NPM1 | EPHX1 4474/4885HIF1A 4859/4885ALDH1A1 4849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.