SCHEMBL6002124

SCHEMBL6002124

CCNS(=O)(=O)c1ccc(OCCCC(=O)O)c2oc(CCNC(=O)/C(C#N)=C(/C)O)cc12

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 11/20 0.37
TSHR P16473 2/20 0.32
HPGD P15428 1/20 0.32
ACLY P53396 1/20 0.31
FABP5 Q01469 6/20 0.31
ALDH1A1 P00352 1/20 0.31
CYSLTR2 Q9NS75 2/20 0.30
CYSLTR1 Q9Y271 2/20 0.30
DHODH Q02127 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6002119 1.00 FABP4 (0.37) FABP4TSHRHPGDACLYFABP5
SCHEMBL4491592 0.84 FABP4 (0.37) FABP4TSHRHPGDACLYCYSLTR2
SCHEMBL4491599 0.84 FABP4 (0.37) FABP4TSHRHPGDACLYCYSLTR2
SCHEMBL4491596 0.84 FABP4 (0.37) FABP4TSHRHPGDACLYCYSLTR2
SCHEMBL4511253 0.70 LTB4R (0.46) FABP4TSHRHPGD
SCHEMBL4511261 0.70 LTB4R (0.46) FABP4TSHRHPGD
SCHEMBL4511259 0.70 LTB4R (0.46) FABP4TSHRHPGD
SCHEMBL10646948 0.66 MAPT (0.46) FABP4HPGDFABP5ALDH1A1
SCHEMBL10647101 0.65 FABP4 (0.44) FABP4FABP5
SCHEMBL10646283 0.64 MAPT (0.44) FABP4TSHRFABP5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060194851-A1 Benzofuran compound and medicinal composition containing the same NEW INDUSTRY RESEARCH ORGANIZATION, THE (JP) 2006-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060194851-A1 Benzofuran compound and medicinal composition containing the same LTB4R2, LTC4S, LTB4R FABP4 747/4885TSHR 4622/4885HPGD 701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.