Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5281604 | 0.81 | HSD17B10 (0.52) | CYP19A1HSD17B10ALDH1A1KDM4ELMNA | |
| SCHEMBL5245026 | 0.78 | GAA (0.58) | CYP19A1HSD17B10ALDH1A1KDM4ELMNA | |
| SCHEMBL6003604 | 0.77 | HSD17B10 (0.53) | CYP19A1HSD17B10ALDH1A1KDM4ELMNA | |
| SCHEMBL5243246 | 0.73 | CYP19A1 (0.59) | CYP19A1HSD17B10ALDH1A1KDM4ELMNA | |
| SCHEMBL5245897 | 0.71 | HSD17B10 (0.55) | CYP19A1HSD17B10ALDH1A1KDM4ELMNA | |
| SCHEMBL8337431 | 0.71 | CA1 (0.58) | CYP19A1HSD17B10ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6003634 | 0.70 | POLB (0.47) | HSD17B10ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL5247351 | 0.68 | KDM4E (0.56) | ALDH1A1KDM4ELMNASMN1; SMN2HTT | |
| SCHEMBL20456972 | 0.67 | HSD11B1 (0.65) | ALDH1A1KDM4EHTTMEN1KMT2A | |
| SCHEMBL5244916 | 0.66 | MAPT (0.65) | HSD17B10ALDH1A1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060199816-A1 | Aryl sulfonyl piperidines | GILLESPIE PAUL | 2006-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199816-A1 | Aryl sulfonyl piperidines | GPR119, SLC5A2, GLS2 | CYP19A1 380/4885HSD17B10 866/4885ALDH1A1 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.