Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5281604 | 0.81 | HSD17B10 (0.52) | HSD17B10KDM4EALDH1A1LMNAGAA | |
| SCHEMBL5243246 | 0.80 | CYP19A1 (0.59) | HSD17B10KDM4EALDH1A1LMNAGAA | |
| SCHEMBL6002179 | 0.77 | CYP19A1 (0.51) | HSD17B10KDM4EALDH1A1LMNAGAA | |
| SCHEMBL8337431 | 0.76 | CA1 (0.58) | HSD17B10ALDH1A1LMNASMN1; SMN2CYP19A1 | |
| SCHEMBL5245897 | 0.74 | HSD17B10 (0.55) | HSD17B10KDM4EALDH1A1LMNAGAA | |
| SCHEMBL5245026 | 0.72 | GAA (0.58) | HSD17B10KDM4EALDH1A1LMNAGAA | |
| SCHEMBL612480 | 0.69 | LMNA (0.63) | HSD17B10ALDH1A1LMNAGAAHTT | |
| SCHEMBL14697013 | 0.68 | HSD17B10 (0.56) | HSD17B10ALDH1A1LMNAGAAPOLB | |
| SCHEMBL613101 | 0.68 | EPHX2 (0.79) | ALDH1A1LMNASMN1; SMN2TSHRHSD11B1 | |
| SCHEMBL7076183 | 0.67 | KMT2A (0.58) | ALDH1A1LMNASMN1; SMN2TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060199816-A1 | Aryl sulfonyl piperidines | GILLESPIE PAUL | 2006-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199816-A1 | Aryl sulfonyl piperidines | GPR119, SLC5A2, GLS2 | HSD17B10 866/4885KDM4E 2675/4885ALDH1A1 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.