Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090928 | 0.83 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9AHPGDKMT2A | |
| SCHEMBL17420472 | 0.80 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL21059152 | 0.80 | SMN1; SMN2 (0.54) | ALDH1A1NPC1RAB9AHPGDKMT2A | |
| SCHEMBL6003092 | 0.79 | RAB9A (0.56) | ALDH1A1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL4824683 | 0.78 | HPGD (0.50) | ALDH1A1HPGDL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL21059158 | 0.78 | SMN1; SMN2 (0.66) | ALDH1A1NPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL734966 | 0.77 | ALDH1A1 (0.72) | ALDH1A1NPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL21059231 | 0.76 | SMN1; SMN2 (0.60) | ALDH1A1NPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL21059212 | 0.75 | SMN1; SMN2 (0.59) | ALDH1A1NPC1RAB9AHPGDL3MBTL1 | |
| SCHEMBL482922 | 0.74 | NPC1 (0.59) | ALDH1A1NPC1RAB9AHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |