SCHEMBL6002463

SCHEMBL6002463

CCc1cc(CC)c(N2CCC[N]CC2)c(CC)c1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28670605 0.74 HTR1A (0.46)
SCHEMBL1969320 0.73 HTR1A (0.35) TP53
SCHEMBL9064915 0.72 SRD5A1 (0.37) TP53
SCHEMBL2095691 0.69 ALDH1A1 (0.46)
SCHEMBL28660347 0.67 KMT2A (0.34) LMNATP53
SCHEMBL2093788 0.66 SMN1; SMN2 (0.38)
SCHEMBL9499633 0.65 KDM4E (0.52) LMNA
SCHEMBL13284470 0.65 KMT2A (0.65) LMNATP53
SCHEMBL19526213 0.65 HTR2A (0.44) LMNA
SCHEMBL2094507 0.65 MAPT (0.38) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1678185-A1 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2006-07-12 EP disclosed
WO-2005042542-A1 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-05-12 WO disclosed