Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | DRD4 | P21917 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
| ▸ | HTR2C | P28335 | 4/20 | 0.35 |
| ▸ | DRD3 | P35462 | 4/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28670605 | 0.84 | HTR1A (0.46) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL28660347 | 0.76 | KMT2A (0.34) | MAPTKDM4ENPC1RAB9AKMT2A | |
| SCHEMBL16386026 | 0.75 | NPSR1 (0.42) | HTR2AMAPTKMT2AMEN1 | |
| SCHEMBL6002463 | 0.73 | LMNA (0.31) | TP53 | |
| SCHEMBL20968795 | 0.73 | POLB (0.38) | — | |
| SCHEMBL28660336 | 0.71 | LMNA (0.46) | MAPTKMT2AMEN1 | |
| SCHEMBL15902670 | 0.67 | MGLL (0.52) | MAPT | |
| SCHEMBL2014395 | 0.65 | DRD2 (0.39) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL14228541 | 0.64 | HTR1A (0.51) | HTR1ADRD2DRD4HTR2AHTR2C | |
| SCHEMBL2228767 | 0.64 | HSPA5 (0.39) | MAPTKDM4ENPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130131343-A1 | MICROWAVE-ASSISTED SYNTHESIS OF N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES | UNIVERSITY OF HAWAII (US) | 2013-05-23 | — | — | US | claimed |
| WO-2011071881-A2 | MICROWAVE-ASSISTED SYNTHESIS OF N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES | UNIVERSITY OF HAWAII (US) | 2011-06-16 | — | — | WO | claimed |
| US-7442800-B2 | Nucleophilic heterocyclic carbene derivatives of Pd(acac)2 for cross-coupling reactions | PROMERUS LLC (US) | 2008-10-28 | — | — | US | claimed |
| US-20060287544-A1 | Nucleophilic heterocyclic carbene derivatives of Pd(acac)2 for cross-coupling reactions | PROMERUS LLC (US) | 2006-12-21 | — | — | US | claimed |
| US-11066434-B2 | Metal complexes comprising aniline type ligands | UMICORE AG & CO. KG | 2021-07-20 | — | — | US | disclosed |
| US-20200239504-A1 | METAL COMPLEXES COMPRISING ANILINE TYPE LIGANDS | UMICORE AG & CO. KG (DE) | 2020-07-30 | — | — | US | disclosed |
| US-20130131343-A1 | MICROWAVE-ASSISTED SYNTHESIS OF N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES | UNIVERSITY OF HAWAII (US) | 2013-05-23 | — | — | US | disclosed |
| WO-2011071881-A2 | MICROWAVE-ASSISTED SYNTHESIS OF N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES | UNIVERSITY OF HAWAII (US) | 2011-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131343-A1 | MICROWAVE-ASSISTED SYNTHESIS OF N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES | NDC1, NUDC, SMARCC2 | HTR1A 1252/4885DRD2 2717/4885DRD4 3008/4885 |
| US-20060287544-A1 | Nucleophilic heterocyclic carbene derivatives of Pd(acac)2 for cross-coupling reactions | NDC1, DDC, PDCD1LG2 | HTR1A 4057/4885DRD2 1366/4885DRD4 1545/4885 |
| US-20200239504-A1 | METAL COMPLEXES COMPRISING ANILINE TYPE LIGANDS | SQLE, SOAT1, SOAT2 | HTR1A 2299/4885DRD2 347/4885DRD4 370/4885 |
| US-11066434-B2 | Metal complexes comprising aniline type ligands | SQLE, SOAT1, SOAT2 | HTR1A 2299/4885DRD2 347/4885DRD4 370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.