Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28670605 | 0.76 | HTR1A (0.46) | KMT2ARAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL1969320 | 0.76 | HTR1A (0.35) | KMT2ARAB9AMAPTGAANPC1 | |
| SCHEMBL28660336 | 0.74 | LMNA (0.46) | KMT2ALMNACYP2C19MAPTHTT | |
| SCHEMBL28670604 | 0.70 | ALDH1A1 (0.45) | KMT2ARAB9ALMNACYP2D6CYP2C19 | |
| SCHEMBL6002463 | 0.67 | LMNA (0.31) | LMNATP53 | |
| SCHEMBL28412268 | 0.64 | ALDH1A1 (0.69) | LMNACYP2D6CYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL27953331 | 0.62 | LMNA (0.54) | KMT2ARAB9ALMNACYP2D6CYP2C19 | |
| SCHEMBL27845814 | 0.61 | MAPT (0.65) | KMT2ARAB9ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL11300055 | 0.61 | — | — | |
| SCHEMBL2226493 | 0.61 | ALDH1A1 (0.73) | KMT2ALMNACYP2D6CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110790728-B | Flexible tripod type polypiperazine dithiocarbazone derivatives, and preparation method and application thereof | 湖北大学 | 2021-11-26 | — | — | CN | disclosed |
| CN-110790728-A | Flexible tripod type polypiperazine dithiocarbazone derivatives, and preparation method and application thereof | 湖北大学 | 2020-02-14 | — | — | CN | disclosed |