Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.46 |
| ▸ | KMO | O15229 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17626003 | 0.79 | KDM4E (0.41) | NPY5RNOTUMIKBKBKDM4EMAPT | |
| SCHEMBL2650383 | 0.76 | IDO1 (0.49) | HRH1NPY5RNOTUMKDM4EALDH1A1 | |
| SCHEMBL28536153 | 0.74 | APP (0.46) | KDM4EMAPTALDH1A1GAAIDO1 | |
| SCHEMBL4044851 | 0.73 | CYP11B1 (0.45) | CYP1B1NOTUMIKBKBKDM4EMAPT | |
| SCHEMBL4047558 | 0.71 | DGAT1 (0.37) | CYP1B1IKBKBMAPTALDH1A1NPC1 | |
| SCHEMBL28536156 | 0.71 | NISCH (0.47) | MAPTALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL4049587 | 0.71 | ALDH1A1 (0.41) | KDM4EMAPTALDH1A1NPC1RAB9A | |
| SCHEMBL2652005 | 0.71 | SMN1; SMN2 (0.38) | NOTUMKDM4EMAPTALDH1A1NPC1 | |
| SCHEMBL4046324 | 0.70 | KMO (0.40) | KMONOTUMALDH1A1NPC1PKM | |
| SCHEMBL29142667 | 0.70 | BRD4 (0.43) | AHRKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |