Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2923881 | 0.84 | TSHR (0.34) | TSHRSMPD3PKM | |
| Hydrochloric Acid SCHEMBL6757419 | 0.82 | TSHR (0.33) | TSHR | |
| SCHEMBL1802878 | 0.80 | — | — | |
| SCHEMBL3944376 | 0.80 | TSHR (0.32) | TSHR | |
| SCHEMBL5971595 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL6759507 | 0.78 | TSHR (0.32) | TSHR | |
| SCHEMBL33881 | 0.77 | CYP1A2 (0.42) | TSHR | |
| SCHEMBL5159269 | 0.77 | POLB (0.40) | TSHR | |
| SCHEMBL3943493 | 0.77 | TSHR (0.34) | TSHR | |
| Bromide SCHEMBL5848621 | 0.77 | HTR2A (0.40) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257249-B1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | WELLA AG (DE) | 2006-11-02 | — | — | EP | claimed |
| US-7018426-B2 | Oxidation dye | WELLA AG (DE) | 2006-03-28 | — | — | US | claimed |
| WO-2005023209-A1 | AGENT AND METHOD FOR DYEING KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2005-03-17 | — | — | WO | claimed |
| EP-1313434-B1 | OXIDATION DYE | WELLA AG (DE) | 2005-01-12 | — | — | EP | claimed |
| US-6793687-B2 | YELLOW AND ORANGE RANGE COLORING | WELLA AKTIENGESELLSCHAFT (DE) | 2004-09-21 | — | — | US | claimed |
| US-6716257-B2 | OXIDATION DYES, WHICH ARE USED FOR TREATMENT OF HUMAN HAIR | WELLA AKTIENGESELLSCHAFT (DE) | 2004-04-06 | — | — | US | claimed |
| EP-1236460-B1 | Bridged diamino pyrazoles and colouring agents containing them | WELLA AG (DE) | 2003-11-26 | — | — | EP | claimed |
| US-20030159222-A1 | Oxidation dye | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-08-28 | — | — | US | claimed |
| US-20030131423-A1 | Diaminopyrazole derivatives and oxidation hair dye containing pyrazolone derivatives | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-07-17 | — | — | US | claimed |
| EP-1313434-A1 | OXIDATION DYE | Wella Aktiengesellschaft (DE) | 2003-05-28 | — | — | EP | claimed |
| US-20020170125-A1 | Bridged diaminopyrazole compounds and dye compositions containing same | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2002-11-21 | — | — | US | claimed |
| EP-1257249-A1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | Wella Aktiengesellschaft (DE) | 2002-11-20 | — | — | EP | claimed |
| WO-2002069919-A1 | OXIDATION DYE | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | claimed |
| WO-2002069918-A1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | claimed |
| EP-1236460-A1 | Bridged diamino pyrazoles and colouring agents containing them | Wella Aktiengesellschaft (DE) | 2002-09-04 | — | — | EP | claimed |
| EP-1257249-B1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | WELLA AG (DE) | 2006-11-02 | — | — | EP | disclosed |
| US-7018426-B2 | Oxidation dye | WELLA AG (DE) | 2006-03-28 | — | — | US | disclosed |
| EP-1257249-A1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | Wella Aktiengesellschaft (DE) | 2002-11-20 | — | — | EP | disclosed |
| WO-2002069919-A1 | OXIDATION DYE | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | disclosed |
| WO-2002069918-A1 | DIAMINOPYRAZOLE DERIVATIVES AND OXIDATION HAIR DYE CONTAINING PYRAZOLONE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030159222-A1 | Oxidation dye | KRT18, NOX4, VIM | TSHR 4742/4885SMPD3 4570/4885PKM 695/4885 |
| US-20030131423-A1 | Diaminopyrazole derivatives and oxidation hair dye containing pyrazolone derivatives | KRT18, AOC1, PPOX | TSHR 4214/4885SMPD3 3940/4885PKM 656/4885 |
| US-20020170125-A1 | Bridged diaminopyrazole compounds and dye compositions containing same | ALK, DDC, CBR1 | TSHR 3885/4885SMPD3 3651/4885PKM 1453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.