Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23657823 | 0.90 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL28592478 | 0.77 | NPC1 (0.43) | RAB9ANPC1 | |
| SCHEMBL2182998 | 0.77 | L3MBTL1 (0.41) | RAB9ASMN1; SMN2TDP1L3MBTL1MEN1 | |
| SCHEMBL28595911 | 0.75 | CHRM1 (0.42) | RAB9ANPC1KCNH2 | |
| SCHEMBL9307047 | 0.69 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL20020162 | 0.69 | MEN1 (0.73) | RAB9ANPC1SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL1221701 | 0.69 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2L3MBTL1KCNH2 | |
| SCHEMBL2098196 | 0.68 | — | — | |
| SCHEMBL1607082 | 0.68 | GAA (0.70) | RAB9ANPC1SMN1; SMN2TDP1L3MBTL1 | |
| Bromide SCHEMBL5963912 | 0.68 | HIF1A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107459510-A | Isoxazole class compound and its application | 华东师范大学 | 2017-12-12 | — | — | CN | disclosed |
| CN-100497345-C | 2, 3-dihydro-6-nitroimidazolo [2,1-b] oxazole compounds for the treatment of tuberculosis | OTSUKA PHARMA CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |