Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31433144 | 0.81 | SMN1; SMN2 (0.53) | RAB9ASMN1; SMN2NPC1TDP1MAPK1 | |
| SCHEMBL7007243 | 0.71 | RAB9A (0.50) | RAB9ASMN1; SMN2NPC1TDP1MAPK1 | |
| SCHEMBL6002649 | 0.69 | RAB9A (0.51) | RAB9ASMN1; SMN2NPC1TDP1MAPK1 | |
| SCHEMBL28996301 | 0.69 | RAB9A (0.51) | RAB9ASMN1; SMN2NPC1TDP1MAPK1 | |
| SCHEMBL10547054 | 0.69 | NPC1 (0.59) | RAB9ASMN1; SMN2NPC1TDP1MAPK1 | |
| SCHEMBL31524105 | 0.68 | — | — | |
| SCHEMBL18404750 | 0.68 | RAB9A (0.51) | RAB9ASMN1; SMN2NPC1TDP1MAPK1 | |
| SCHEMBL28564941 | 0.67 | SMN1; SMN2 (0.63) | RAB9ASMN1; SMN2NPC1TDP1MAPK1 | |
| SCHEMBL850999 | 0.65 | APP (0.78) | RAB9ASMN1; SMN2L3MBTL1ALDH1A1MAPT | |
| Benzylphenylether SCHEMBL61660 | 0.65 | LMNA (0.74) | RAB9ASMN1; SMN2L3MBTL1MAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326774-A | 3-methyl-5-(2-(3-tert-butylamino-2-hydroxypropoxy)phenoxy-methyl) -1,2,4-oxadiazole hydrochloride | MASHOVSKY MIKHAIL D | 1994-07-05 | — | — | US | disclosed |
| WO-1993009106-A1 | DERIVATIVES OF 5-PHENOXYMETHYL-1,2,4-OXADIAZOL, THEIR SALTS, METHOD OF OBTAINING THEM AND A PHARMACEUTICAL PREPARATION WITH ANTIHYPERTENSIVE, ANTIANGINAL, ANTIARRHYTHMIC AND ANTIGLAUCOMATOMIC PROPERTIES BASED ON THEM | TSENTR PO KHIMII LEKARSTVENNYKH SREDSTV (SU) | 1993-05-13 | — | — | WO | disclosed |
| WO-1993009106-A1 | DERIVATIVES OF 5-PHENOXYMETHYL-1,2,4-OXADIAZOL, THEIR SALTS, METHOD OF OBTAINING THEM AND A PHARMACEUTICAL PREPARATION WITH ANTIHYPERTENSIVE, ANTIANGINAL, ANTIARRHYTHMIC AND ANTIGLAUCOMATOMIC PROPERTIES BASED ON THEM | TSENTR PO KHIMII LEKARSTVENNYKH SREDSTV (SU) | 1993-05-13 | — | — | WO | disclosed |