Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315559 | 0.79 | CES2 (0.52) | TSHRALOX15CES2CES1SRD5A2 | |
| SCHEMBL6002650 | 0.79 | CES2 (0.52) | TSHRALOX15CES2CES1SRD5A2 | |
| SCHEMBL11105093 | 0.78 | TSHR (0.50) | TSHRALOX15CES2CES1SRD5A2 | |
| SCHEMBL7555313 | 0.77 | TSHR (0.55) | TSHRALOX15CES2CES1SRD5A2 | |
| SCHEMBL6493746 | 0.76 | CES2 (0.60) | TSHRALOX15CES2CES1SRD5A2 | |
| 4-Chloro-Benzoic Acid SCHEMBL6444124 | 0.76 | TSHR (0.85) | TSHRALOX15CES2CES1SRD5A2 | |
| 1,4-Dichlorobenzene SCHEMBL76049 | 0.75 | ALOX15 (0.60) | TSHRALOX15CES2CES1SRD5A2 | |
| SCHEMBL17187946 | 0.74 | MAPT (0.69) | TSHRALOX15CES2CES1SRD5A2 | |
| SCHEMBL75640 | 0.74 | MAPT (0.69) | TSHRALOX15CES2CES1SRD5A2 | |
| SCHEMBL7959261 | 0.74 | CES2 (0.48) | TSHRALOX15CES2CES1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897333-B2 | Process for the preparation of fibrates | SOLCHEM ITALIANA S.P.A. (IL) | 2005-05-24 | — | — | US | claimed |
| CN-1608076-A | Synthesis of 2-aralkyloxyadenosine and 2-alkoxyadenosine | KING PHARMACEUTICALS RES & DEV (US) | 2005-04-20 | — | — | CN | claimed |
| CN-1018548-B | CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-07 | — | — | CN | claimed |
| CN-101448836-B | Pyridopyrimidinone derivatives | HOFFMAN-LA ROCHE LTD. (CH) | 2011-12-14 | — | — | CN | disclosed |
| CN-101448836-A | Pyridopyrimidinone derivatives | HOFFMANN LA ROCHE (CH) | 2009-06-03 | — | — | CN | disclosed |
| CN-101268064-A | Pyrazine derivatives useful as adenosine receptor antagonists | ALMIRALL LAB (ES) | 2008-09-17 | — | — | CN | disclosed |
| CN-1296349-C | Novel propionic acid derivatives | ASAHI KASEI PHARMA CORP (JP) | 2007-01-24 | — | — | CN | disclosed |
| CN-1263751-C | Novel compounds | ASTRAZENECA AB (SE) | 2006-07-12 | — | — | CN | disclosed |
| CN-1649834-A | Novel propionic acid derivatives | ASAHI KASEI PHARMA CORP (JP) | 2005-08-03 | — | — | CN | disclosed |
| CN-1608076-A | Synthesis of 2-aralkyloxyadenosine and 2-alkoxyadenosine | KING PHARMACEUTICALS RES & DEV (US) | 2005-04-20 | — | — | CN | disclosed |
| CN-1541214-A | Novel compounds | — | 2004-10-27 | — | — | CN | disclosed |
| CN-1018548-B | CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-07 | — | — | CN | disclosed |
| CN-88100219-A | New carboxylic acid derivative and preparation technology thereof and the medicinal compositions that contains these derivatives | — | 1988-07-27 | — | — | CN | disclosed |