Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6538855 | 0.83 | PPARG (0.44) | MTNR1AMTNR1BALDH1A1SLC6A4LTA4H | |
| SCHEMBL6002554 | 0.79 | PPARG (0.46) | ALDH1A1SLC6A4LTA4HTDP1PPARG | |
| SCHEMBL18343712 | 0.78 | LTA4H (0.44) | ALDH1A1SLC6A4LTA4HMAPK1TDP1 | |
| SCHEMBL1109844 | 0.77 | SLC6A4 (0.39) | MTNR1AMTNR1BTSHRALDH1A1MAPT | |
| SCHEMBL8386314 | 0.77 | LTA4H (0.43) | ALDH1A1SLC6A4LTA4HMAPK1PPARG | |
| SCHEMBL2186074 | 0.76 | CA4 (0.42) | MTNR1AMTNR1BTSHRALDH1A1MAPT | |
| SCHEMBL7960172 | 0.76 | TSHR (0.42) | MTNR1AMTNR1BTSHRALDH1A1MAPT | |
| SCHEMBL1356899 | 0.76 | PPARG (0.51) | PPARGPPARA | |
| SCHEMBL257324 | 0.74 | MTNR1A (0.52) | MTNR1AMTNR1BMAPTSLC6A4LTA4H | |
| SCHEMBL5575610 | 0.74 | LTA4H (0.40) | MTNR1AMTNR1BTSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | claimed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | claimed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | claimed |
| EP-0274907-B1 | ANIONIC END-CAPPED OLIGOMERIC ESTERS AS SOIL RELEASE AGENTS IN DETERGENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1992-08-12 | — | — | EP | claimed |
| EP-0274907-A1 | Anionic end-capped oligomeric esters as soil release agents in detergent compositions | THE PROCTER & GAMBLE COMPANY (US) | 1988-07-20 | — | — | EP | claimed |
| US-4721580-A | TEREPHTHALATE ESTERS WITHSODIUM SULFONATE END GROUPS | THE PROCTER & GAMBLE COMPANY (US) | 1988-01-26 | — | — | US | claimed |
| US-4331805-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1982-05-25 | — | — | US | claimed |
| US-4302586-A | FLUORESCENT WHITENERS | CIBA-GEIGY CORPORATION (US) | 1981-11-24 | — | — | US | claimed |
| US-4157443-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1979-06-05 | — | — | US | claimed |
| US-11040028-B2 | Penicinotam derivative, preparation method and use thereof | OCEAN UNIVERSITY OF CHINA (CN) | 2021-06-22 | — | — | US | disclosed |
| US-10993938-B2 | Lactam compound, preparation method and use thereof | OCEAN UNIVERSITY OF CHINA (CN) | 2021-05-04 | — | — | US | disclosed |
| US-20210008045-A1 | PANICINOTAM DERIVATIVE, PREPARATION METHOD AND USE THEREOF | OCEAN UNIVERSITY OF CHINA (CN) | 2021-01-14 | — | — | US | disclosed |
| US-20200030312-A1 | Lactam Compound, Preparation Method and Use thereof | OCEAN UNIVERSITY OF CHINA (CN) | 2020-01-30 | — | — | US | disclosed |
| EP-3169671-B1 | 1-(5-(TERT.-BUTYL)ISOXAZOL-3-YL)-3-(4-((PHENYL)ETHYNYL)PHENYL)UREA DERIVATIVES AND RELATED COMPOUNDS AS FLT3 INHIBITORS FOR TREATING CANCER | SUNSHINE LAKE PHARMA CO LTD (CN) | 2019-08-21 | — | — | EP | disclosed |
| US-4686230-A | Picoline derivative useful as gastric acid secretion inhibitors | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1987-08-11 | — | — | US | disclosed |
| US-4331805-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1982-05-25 | — | — | US | disclosed |
| US-4302586-A | FLUORESCENT WHITENERS | CIBA-GEIGY CORPORATION (US) | 1981-11-24 | — | — | US | disclosed |
| US-4236003-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1980-11-25 | — | — | US | disclosed |
| US-4203757-A | Halophenoxyalkoxy phosphorous-containing sulfides | GAF CORPORATION (US) | 1980-05-20 | — | — | US | disclosed |
| US-4157443-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1979-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200030312-A1 | Lactam Compound, Preparation Method and Use thereof | FURIN, PEPD, PIN1 | MTNR1A 4188/4885MTNR1B 3821/4885TSHR 4676/4885 |
| US-10993938-B2 | Lactam compound, preparation method and use thereof | FURIN, PEPD, PIN1 | MTNR1A 4188/4885MTNR1B 3821/4885TSHR 4676/4885 |
| US-11040028-B2 | Penicinotam derivative, preparation method and use thereof | TPMT, MAPT, TLR4 | MTNR1A 2436/4885MTNR1B 2806/4885TSHR 3737/4885 |
| US-20210008045-A1 | PANICINOTAM DERIVATIVE, PREPARATION METHOD AND USE THEREOF | TPMT, PBRM1, PGM2 | MTNR1A 1758/4885MTNR1B 2042/4885TSHR 2270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.