Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2093140 | 0.85 | ALDH1A1 (0.36) | LTA4HALDH1A1HPGDHTT | |
| SCHEMBL2092687 | 0.85 | LTA4H (0.31) | LTA4H | |
| SCHEMBL2098331 | 0.82 | SLC6A3 (0.33) | ALDH1A1 | |
| SCHEMBL2093799 | 0.80 | SLC6A3 (0.33) | ALDH1A1 | |
| SCHEMBL2093346 | 0.80 | — | — | |
| SCHEMBL357112 | 0.76 | — | — | |
| SCHEMBL2097743 | 0.72 | ALDH1A1 (0.34) | LTA4HALDH1A1HPGDHTT | |
| SCHEMBL2097641 | 0.70 | CES2 (0.31) | — | |
| SCHEMBL2091687 | 0.69 | ALDH1A1 (0.33) | LTA4HALDH1A1HPGDHTT | |
| SCHEMBL2097744 | 0.69 | ALDH1A1 (0.33) | LTA4HALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |