Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 3/20 | 0.43 |
| ▸ | ATP4B | P51164 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | RARA | P10276 | 2/20 | 0.39 |
| ▸ | RARB | P10826 | 2/20 | 0.39 |
| ▸ | RARG | P13631 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002435 | 0.78 | ALOX5 (0.45) | KDM4ENPC1ALDH1A1LMNACOMT | |
| SCHEMBL5544025 | 0.76 | HRH3 (0.42) | ATP4AATP4BHRH3RARARARB | |
| SCHEMBL19196100 | 0.74 | RARA (0.46) | HRH3RARARARBRARGNPC1 | |
| SCHEMBL3880439 | 0.71 | RARA (0.48) | HRH3RARARARBRARGNPC1 | |
| SCHEMBL27629310 | 0.71 | DHFR (0.47) | ATP4AATP4BHRH3RARARARB | |
| SCHEMBL2091544 | 0.69 | HRH3 (0.46) | HRH3RARARARBRARGALDH1A1 | |
| SCHEMBL19938082 | 0.68 | RARA (0.48) | ATP4AATP4BHRH3RARARARB | |
| SCHEMBL2090545 | 0.68 | HRH3 (0.45) | HRH3RARARARBRARGNPC1 | |
| SCHEMBL5167355 | 0.67 | CYP17A1 (0.49) | HRH3KDM4ESMN1; SMN2 | |
| SCHEMBL2093689 | 0.67 | RARA (0.47) | HRH3RARARARBRARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |