Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852110 | 0.83 | ADORA2A (0.55) | ADORA3ADORA2AADORA2BADORA1ALDH1A1 | |
| SCHEMBL11273216 | 0.76 | ADORA3 (0.48) | ADORA3ADORA2AADORA2BADORA1RAB9A | |
| SCHEMBL69810 | 0.75 | ADORA3 (1.00) | ADORA3ADORA2AADORA2BADORA1ALDH1A1 | |
| SCHEMBL3252621 | 0.74 | ADORA3 (0.68) | ADORA3ADORA2AADORA2BADORA1ALDH1A1 | |
| SCHEMBL9852187 | 0.72 | ADORA3 (0.55) | ADORA3ADORA2AADORA2BADORA1CYP19A1 | |
| SCHEMBL9108544 | 0.72 | ADORA3 (0.66) | ADORA3ADORA2AADORA2BADORA1ALDH1A1 | |
| SCHEMBL11332250 | 0.72 | ADORA3 (0.66) | ADORA3ADORA2AADORA2BADORA1ALDH1A1 | |
| SCHEMBL9852272 | 0.72 | ADORA3 (0.66) | ADORA3ADORA2AADORA2BADORA1LMNA | |
| SCHEMBL10391988 | 0.71 | ADORA2A (0.49) | ADORA3ADORA2AADORA2BADORA1ALDH1A1 | |
| SCHEMBL18377841 | 0.71 | ADORA3 (0.53) | ADORA3ADORA2AADORA2BADORA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7092608-B2 | Polyimide optical materials, polyimide precursor solutions and optical waveguide elements | KABUSHIKI KAISHA TOSHIBA (JP) | 2006-08-15 | — | — | US | disclosed |
| US-7082244-B2 | Polyimide optical materials, polyimide precursor solutions and optical waveguide elements | KABUSHIKI KAISHA TOSHIBA (JP) | 2006-07-25 | — | — | US | disclosed |
| US-20060159413-A1 | POLYIMIDE OPTICAL MATERIALS, POLYIMIDE PRECURSOR SOLUTIONS AND OPTICAL WAVEGUIDE ELEMENTS | KABUSHIKI KAISHA TOSHIBA (JP) | 2006-07-20 | — | — | US | disclosed |
| US-20040197064-A1 | Polyimide optical materials, polyimide precursor solutions and optical waveguide elements | KABUSHIKI KAISHA TOSHIBA (JP) | 2004-10-07 | — | — | US | disclosed |