SCHEMBL69810

SCHEMBL69810

Nc1nc(-c2ccccc2)ns1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 5/20 1.00
ADORA2A P29274 4/20 1.00
ADORA1 P30542 4/20 1.00
ADORA2B P29275 3/20 1.00
RAB9A P51151 5/20 0.52
NPC1 O15118 4/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
CASP3 P42574 1/20 0.52
SENP8 Q96LD8 1/20 0.52
SENP7 Q9BQF6 1/20 0.52
SENP6 Q9GZR1 1/20 0.52
POLB P06746 2/20 0.50
CYP19A1 P11511 1/20 0.47
SMN1; SMN2 Q16637 5/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HTT P42858 2/20 0.45
ALDH1A1 P00352 2/20 0.45
ALOX15 P16050 1/20 0.44
NOTUM Q6P988 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL4114413 0.85 ADORA3 (0.72) ADORA3ADORA2AADORA1ADORA2BRAB9A
SCHEMBL3252621 0.81 ADORA3 (0.68) ADORA3ADORA2AADORA1ADORA2BRAB9A
SCHEMBL9108544 0.79 ADORA3 (0.66) ADORA3ADORA2AADORA1ADORA2BRAB9A
SCHEMBL11332250 0.79 ADORA3 (0.66) ADORA3ADORA2AADORA1ADORA2BMEN1
SCHEMBL20390138 0.79 ADORA3 (0.66) ADORA3ADORA2AADORA1ADORA2BRAB9A
SCHEMBL20390644 0.79 ADORA3 (0.66) ADORA3ADORA2AADORA1ADORA2BRAB9A
SCHEMBL9852272 0.79 ADORA3 (0.66) ADORA3ADORA2AADORA1ADORA2BRAB9A
SCHEMBL16238754 0.79 ADORA3 (0.66) ADORA3ADORA2AADORA1ADORA2BRAB9A
SCHEMBL30585815 0.79 CYP19A1 (0.67) ADORA3ADORA2AADORA1ADORA2BMEN1
SCHEMBL9230808 0.79 CYP19A1 (0.67) ADORA3ADORA2AADORA1ADORA2BMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 325 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230072612-A1 FLAME RETARDANT CHEMICAL COMPOSITIONS NORDTREAT FINLAND OY (FI) 2023-03-09 US claimed
EP-4097176-A1 FLAME RETARDANT CHEMICAL COMPOSITIONS Nordtreat Finland OY (FI) 2022-12-07 EP claimed
CN-115087697-A Flame retardant chemical composition 诺德特利特芬兰公司 2022-09-20 CN claimed
US-11292968-B2 Sulfenamides as flame retardants SONGWON INTERNATIONAL AG (CH) 2022-04-05 US claimed
CN-110872384-B Flame retardant composition, use thereof and method for the production thereof 松原国际股份有限公司 2022-02-25 CN claimed
WO-2021151493-A1 FLAME RETARDANT CHEMICAL COMPOSITIONS NORDTREAT FINLAND OY (FI) 2021-08-05 WO claimed
EP-3066153-B1 SULFENAMIDES AS FLAME RETARDANTS SONGWON INT AG (CH) 2020-05-06 EP claimed
CN-110872384-A Flame retardant composition, use thereof and method for the production thereof 松原国际股份有限公司 2020-03-10 CN claimed
CN-105829430-B Sulfenamides as flame retardants 松原国际股份有限公司 2019-11-15 CN claimed
US-20160289566-A1 SULFENAMIDES AS FLAME RETARDANTS SONGWON INTERNATIONAL AG (CH) 2016-10-06 US claimed
EP-1937652-A1 PYRIMIDINE AMIDE COMPOUNDS AS PGDS INHIBITORS Aventis Pharmaceuticals Inc. (US) 2008-07-02 EP claimed
WO-2007041634-A1 PYRIMIDINE AMIDE COMPOUNDS AS PGDS INHIBITORS AVENTIS PHARMACEUTICALS INC. (US) 2007-04-12 WO claimed
EP-0272212-B1 PROCESS FOR CONTINUALLY PRODUCING AZO OR HYDRAZONE DYES CIBA-GEIGY AG (CH) 1993-09-01 EP claimed
US-4925926-A Preparation of cationic azo or hydrazone dyes in which the alkylation and the separation of the cationic dye are carried out continuously CIBA-GEIGY CORPORATION (US) 1990-05-15 US claimed
US-4810397-A ALUMINUM COMPOUND, ACID, THIADIAZOLE OR TRIAZOLE UNION OIL COMPANY OF CALIFORNIA (US) 1989-03-07 US claimed
EP-0272212-A2 Process for continually producing azo or hydrazone dyes CIBA-GEIGY AG (CH) 1988-06-22 EP claimed
US-4719001-A ALUMINUM COMPOUND AND THIADIAZOLE DERIVATIVE UNION OIL COMPANY OF CALIFORNIA (US) 1988-01-12 US claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
US-4217271-A Basic azo dyestuffs containing a n-picolinium alkylene amino phenyl group IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-08-12 US claimed
US-4028323-A WITH A SUBSTITUTED AMINOBENZENE CIBA-GEIGY AG (CH) 1977-06-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160289566-A1 SULFENAMIDES AS FLAME RETARDANTS STS, TST, PFAS ADORA3 3578/4885ADORA2A 4029/4885ADORA1 4148/4885
US-11292968-B2 Sulfenamides as flame retardants STS, TST, PFAS ADORA3 3578/4885ADORA2A 4029/4885ADORA1 4148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.