Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | BID | P55957 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6394159 | 0.89 | ADRA2A (0.43) | CYP4F2CYP4A11ADRA2AADRA2BADRA2C | |
| SCHEMBL5984175 | 0.83 | GABRA1 (0.41) | — | |
| SCHEMBL15162504 | 0.79 | LIPG (0.46) | LIPGCYP3A4CYP2D6CYP2C9THRA | |
| SCHEMBL5513811 | 0.78 | L3MBTL1 (0.49) | CYP3A4CYP2C9ADRA2A | |
| SCHEMBL245188 | 0.78 | LIPG (0.56) | LIPGCYP3A4CYP2D6CYP2C9TYR | |
| SCHEMBL29520482 | 0.78 | LIPG (0.56) | LIPGCYP3A4CYP2D6CYP2C9TYR | |
| SCHEMBL29315000 | 0.77 | LIPG (0.44) | LIPGCYP3A4CYP2D6CYP2C9THRA | |
| SCHEMBL9389206 | 0.76 | CYP4F2 (0.47) | LIPGCYP3A4CYP2D6CYP2C9THRA | |
| SCHEMBL1087070 | 0.76 | LIPG (0.50) | LIPGCYP3A4CYP2D6CYP2C9TYR | |
| Benzene SCHEMBL3118223 | 0.76 | LIPG (0.54) | LIPGCYP3A4CYP2D6CYP2C9TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |