Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698892 | 1.00 | MAPT (0.42) | MAPTLMNAALDH1A1NPSR1KMT2A | |
| SCHEMBL7700542 | 0.91 | POLB (0.43) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL6003297 | 0.91 | POLB (0.43) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL7220418 | 0.80 | ALDH1A1 (0.40) | LMNAALDH1A1POLBFNTAFNTB | |
| SCHEMBL7236823 | 0.76 | FNTA (0.42) | FNTAFNTBPGGT1B | |
| SCHEMBL7220168 | 0.71 | FNTA (0.37) | LMNAALDH1A1POLBFNTAFNTB | |
| Hydrochloric Acid SCHEMBL7220321 | 0.71 | FNTA (0.41) | FNTAFNTBPGGT1B | |
| SCHEMBL7736904 | 0.71 | S1PR3 (0.42) | FNTAFNTBPGGT1B | |
| SCHEMBL7222558 | 0.69 | S1PR3 (0.37) | FNTAFNTBPGGT1B | |
| SCHEMBL7673750 | 0.69 | FNTA (0.44) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060199816-A1 | Aryl sulfonyl piperidines | GILLESPIE PAUL | 2006-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199816-A1 | Aryl sulfonyl piperidines | GPR119, SLC5A2, GLS2 | MAPT 4530/4885LMNA 3687/4885ALDH1A1 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.