Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6003297 | 1.00 | POLB (0.43) | POLBLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7698892 | 0.91 | MAPT (0.42) | POLBLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6003410 | 0.91 | MAPT (0.42) | POLBLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7241410 | 0.75 | FNTA (0.42) | FNTAFNTBPGGT1B | |
| SCHEMBL7228470 | 0.74 | TRPV4 (0.35) | KMT2AFNTAFNTBPGGT1BMAPT | |
| Hydrochloric Acid SCHEMBL7220321 | 0.72 | FNTA (0.41) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL7736904 | 0.72 | S1PR3 (0.42) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL7736898 | 0.72 | PKM (0.35) | LMNAKMT2AALDH1A1TSHRFNTA | |
| SCHEMBL7673750 | 0.70 | FNTA (0.44) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL7220418 | 0.70 | ALDH1A1 (0.40) | POLBLMNAALDH1A1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002020015-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2002-03-14 | — | — | WO | disclosed |