SCHEMBL6003603

SCHEMBL6003603

Nc1nnoc1-c1ccccc1-c1onnc1N

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
KDM4E B2RXH2 4/20 0.37
SMARCA2 P51531 2/20 0.32
SMARCA4 P51532 2/20 0.32
PBRM1 Q86U86 2/20 0.32
TDO2 P48775 1/20 0.32
HPGD P15428 3/20 0.32
GAA P10253 2/20 0.32
HSD17B10 Q99714 2/20 0.32
MAPT P10636 1/20 0.32
SMN1; SMN2 Q16637 4/20 0.32
NPC1 O15118 3/20 0.32
RAB9A P51151 3/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
BRD4 O60885 1/20 0.31
NR1I2 O75469 1/20 0.31
KIT P10721 1/20 0.31
KDR P35968 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11712592 0.80 NR4A2 (0.42) ALDH1A1KDM4ESMARCA2SMARCA4PBRM1
SCHEMBL8754426 0.74 NPC1 (0.31) ALDH1A1L3MBTL1HPGDMAPTSMN1; SMN2
SCHEMBL6003605 0.73 ALDH1A1 (0.40) ALDH1A1L3MBTL1KDM4ETDO2HPGD
SCHEMBL12237786 0.71 ALDH1A1 (0.50) ALDH1A1L3MBTL1KDM4EHPGDGAA
SCHEMBL9176881 0.67 ALDH1A1 (0.48) ALDH1A1L3MBTL1KDM4ESMARCA2SMARCA4
SCHEMBL2200423 0.67 GPR55 (0.42) ALDH1A1L3MBTL1KDM4ETDO2HPGD
SCHEMBL11673806 0.63 RAB9A (0.47) ALDH1A1KDM4EHPGDGAAHSD17B10
SCHEMBL2200421 0.63 GPR55 (0.42) ALDH1A1TDO2HPGDHSD17B10MAPT
Ammonia Solution, Strong SCHEMBL21297045 0.63 ALDH1A1 (0.93) ALDH1A1L3MBTL1KDM4EHPGDGAA
SCHEMBL5152914 0.62 ADORA2A (0.45) ALDH1A1L3MBTL1KDM4ETDO2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7092608-B2 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2006-08-15 US claimed
US-20060159413-A1 POLYIMIDE OPTICAL MATERIALS, POLYIMIDE PRECURSOR SOLUTIONS AND OPTICAL WAVEGUIDE ELEMENTS KABUSHIKI KAISHA TOSHIBA (JP) 2006-07-20 US claimed
US-7092608-B2 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2006-08-15 US disclosed
US-7082244-B2 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2006-07-25 US disclosed
US-20060159413-A1 POLYIMIDE OPTICAL MATERIALS, POLYIMIDE PRECURSOR SOLUTIONS AND OPTICAL WAVEGUIDE ELEMENTS KABUSHIKI KAISHA TOSHIBA (JP) 2006-07-20 US disclosed
US-20040197064-A1 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2004-10-07 US disclosed