SCHEMBL2200421

SCHEMBL2200421

c1ccc(-c2ccccc2-c2nnoc2-c2ccccc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR55 Q9Y2T6 1/20 0.42
ALDH1A1 P00352 5/20 0.37
MAPT P10636 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
TSHR P16473 2/20 0.37
HTT P42858 1/20 0.37
TDO2 P48775 2/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
PKM P14618 1/20 0.36
MAOB P27338 1/20 0.36
AGTR1 P30556 1/20 0.36
NR4A2 P43354 1/20 0.35
ABCG2 Q9UNQ0 1/20 0.35
DCUN1D2 Q6PH85 1/20 0.35
DCUN1D1 Q96GG9 1/20 0.35
POLB P06746 1/20 0.35
HSD17B10 Q99714 2/20 0.34
HPGD P15428 1/20 0.34
BCL2L1 Q07817 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4051106 0.92 GPR55 (0.42) GPR55ALDH1A1MAPTSMN1; SMN2TSHR
SCHEMBL2200423 0.85 GPR55 (0.42) GPR55ALDH1A1MAPTSMN1; SMN2TSHR
SCHEMBL29872659 0.84 L3MBTL1 (0.49) ALDH1A1MAPTSMN1; SMN2TSHRNPC1
SCHEMBL9176881 0.84 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2TDO2NPC1RAB9A
SCHEMBL1175088 0.84 NR4A2 (0.44) ALDH1A1SMN1; SMN2HTTNPC1RAB9A
SCHEMBL186399 0.82 NR4A2 (0.42) ALDH1A1SMN1; SMN2HTTNPC1RAB9A
SCHEMBL8754426 0.81 NPC1 (0.31) ALDH1A1MAPTSMN1; SMN2NPC1RAB9A
SCHEMBL6853260 0.81 L3MBTL1 (0.34) ALDH1A1SMN1; SMN2TSHRNPC1RAB9A
SCHEMBL10709249 0.81 ATR (0.40) GPR55ALDH1A1MAPTSMN1; SMN2TSHR
SCHEMBL11338967 0.77 SOAT1 (0.38) ALDH1A1MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240016018-A1 DISPLAY DEVICE AND PREPARATION METHOD THEREFOR TCL TECHNOLOGY GROUP CORPORATION (CN) 2024-01-11 US claimed
US-20240016018-A1 DISPLAY DEVICE AND PREPARATION METHOD THEREFOR TCL TECHNOLOGY GROUP CORPORATION (CN) 2024-01-11 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20080102311-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-05-01 US disclosed
EP-0478599-B1 DETECTION MATERIAL FOR IONIZING RADIATION WALLAC OY (FI) 1996-09-04 EP disclosed
US-5243193-A DETECTION MATERIAL FOR IONIZING RADIATION WALLAC OY (FI) 1993-09-07 US disclosed
EP-0478599-A1 DETECTION MATERIAL FOR IONIZING RADIATION. WALLAC OY (FI) 1992-04-08 EP disclosed
WO-1991009326-A1 ELASTIC SCINTILLATOR MATERIAL WALLAC OY (FI) 1991-06-27 WO disclosed
WO-1990016002-A1 DETECTION MATERIAL FOR IONIZING RADIATION WALLAC OY (FI) 1990-12-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080102311-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME L1CAM, EML4, EBPL GPR55 4635/4885ALDH1A1 675/4885MAPT 778/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.