SCHEMBL6003905

SCHEMBL6003905

O=C(O)CCSCSCCC(=O)O

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.77
KMT2A Q03164 1/20 0.77
HSD17B10 Q99714 1/20 0.77
TDP1 Q9NUW8 1/20 0.77
BHMT Q93088 3/20 0.64
TSHR P16473 3/20 0.61
CYP2C19 P33261 1/20 0.48
EGLN1 Q9GZT9 2/20 0.47
ALKBH5 Q6P6C2 1/20 0.47
SUCNR1 Q9BXA5 1/20 0.47
CYP1A2 P05177 1/20 0.44
SLC22A6 Q4U2R8 1/20 0.42
NFKB1 P19838 1/20 0.40
PMP22 Q01453 1/20 0.40
CYP2D6 P10635 1/20 0.40
HIF1A Q16665 1/20 0.40
APEX1 P27695 1/20 0.39
FFAR3 O14843 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC1 Q13547 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11155757 0.97 LMNA (0.72) LMNAKMT2AHSD17B10TDP1BHMT
SCHEMBL10482292 0.89 LMNA (0.62) LMNAKMT2AHSD17B10TDP1BHMT
SCHEMBL10482221 0.89 LMNA (0.62) LMNAKMT2AHSD17B10TDP1BHMT
E388 SCHEMBL28696 0.87 LMNA (1.00) LMNAKMT2AHSD17B10TDP1BHMT
E388 SCHEMBL28962323 0.87 LMNA (1.00) LMNAKMT2AHSD17B10TDP1BHMT
E388 SCHEMBL341724 0.84 LMNA (0.93) LMNAKMT2AHSD17B10TDP1BHMT
E388 SCHEMBL21494504 0.84 LMNA (0.93) LMNAKMT2AHSD17B10TDP1BHMT
E388 SCHEMBL9715444 0.84 LMNA (0.93) LMNAKMT2AHSD17B10TDP1BHMT
E388 SCHEMBL9715431 0.84 LMNA (0.93) LMNAKMT2AHSD17B10TDP1BHMT
E388 SCHEMBL11415832 0.84 LMNA (0.93) LMNAKMT2AHSD17B10TDP1BHMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12419551-B2 Mediation of in vivo analyte signal degradation SENSEONICS, INCORPORATED (US) 2025-09-23 US claimed
EP-3965657-B1 MEDIATION OF IN VIVO ANALYTE SIGNAL DEGRADATION SENSEONICS INC (US) 2025-03-05 EP claimed
CN-115300637-A Chalcogen hybrid bond bridged dimer prodrug, self-assembled nanoparticles thereof, preparation method and application 沈阳药科大学 2022-11-08 CN claimed
JP-1226811-A None JP disclosed
US-20260008997-A1 CELL CULTURE COMPOSITIONS WITH ANTIOXIDANTS AND METHODS FOR POLYPEPTIDE PRODUCTION GENENTECH, INC. (US) 2026-01-08 US disclosed
EP-2970875-B2 CELL CULTURE COMPOSITIONS WITH ANTIOXIDANTS AND METHODS FOR POLYPEPTIDE PRODUCTION HOFFMANN LA ROCHE (CH) 2025-11-26 EP disclosed
US-12419551-B2 Mediation of in vivo analyte signal degradation SENSEONICS, INCORPORATED (US) 2025-09-23 US disclosed
EP-3965657-B1 MEDIATION OF IN VIVO ANALYTE SIGNAL DEGRADATION SENSEONICS INC (US) 2025-03-05 EP disclosed
CN-115300637-B Chalcogen hybrid bond bridged dimer prodrug, self-assembled nanoparticle thereof, preparation method and application 沈阳药科大学 2024-03-29 CN disclosed
CN-115300637-A Chalcogen hybrid bond bridged dimer prodrug, self-assembled nanoparticles thereof, preparation method and application 沈阳药科大学 2022-11-08 CN disclosed
CN-114703244-A Method for reducing trisulfide bonds during recombinant production of polypeptides 豪夫迈·罗氏有限公司 2022-07-05 CN disclosed
EP-0327306-A2 Leukotriene B4 antagonists SMITHKLINE BEECHAM CORPORATION (US) 1989-08-09 EP disclosed
US-4730005-A DITHIA-ALKANEDIOIC ACIDS SMITHKLINE BECKMAN CORPORATION (US) 1988-03-08 US disclosed
EP-0168902-B1 LEUKOTRIENE ANTAGONISTS SMITHKLINE BECKMAN CORPORATION (US) 1987-09-30 EP disclosed
EP-0153009-B1 LEUKOTRIENE ANTAGONISTS SMITHKLINE BECKMAN CORPORATION (US) 1987-01-07 EP disclosed
US-4623535-A ANTIASTHMA SMITHKLINE BECKMAN CORPORATION (US) 1986-11-18 US disclosed
EP-0168902-A1 Leukotriene antagonists SMITHKLINE BECKMAN CORPORATION (US) 1986-01-22 EP disclosed
EP-0153009-A1 Leukotriene antagonists SMITHKLINE BECKMAN CORPORATION (US) 1985-08-28 EP disclosed
US-4523024-A STABILIZERS FOR ORGANIC MATERIALS SENSITIVE TO HEAT, LIGHT, AND/OR OXIDATIVE FACTORS KURARAY CO., LTD. (JP) 1985-06-11 US disclosed
EP-0113042-A2 3,4-Dihydro-2H-benzopyran derivatives, a method of producing them, a method of using them as stabilizers for organic materials, and organic compositions containing such stabilizers KURARAY CO., LTD. (JP) 1984-07-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12419551-B2 Mediation of in vivo analyte signal degradation SLC2A1, TXN2, SLC2A8 LMNA 4443/4885KMT2A 4370/4885HSD17B10 1692/4885
US-20260008997-A1 CELL CULTURE COMPOSITIONS WITH ANTIOXIDANTS AND METHODS FOR POLYPEPTIDE PRODUCTION CD99, BHMT, PROC LMNA 1603/4885KMT2A 3095/4885HSD17B10 3931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.